EEG Characteristics and Postoperative Delirium

NCT ID: NCT06102967

Last Updated: 2024-08-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

66 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-10-01

Study Completion Date

2024-07-01

Brief Summary

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The goal of this \[type of study: observational study \] is to \[compare Energy differences in various bands of intraoperative electroencephalogram in elderly patients with postoperative delirium and non delirium.\] in \[describe participant population selected 69 patients who underwent laparoscopic radical surgery for colorectal cancer on a selective basis\]. The main question\[s\] it aims to answer are:

• \[Is there any difference in the spectral range of EEG between POD patients and non POD patients\] Participants will \[Cognitive.•Postoperative delirium.•Preoperative weakness.\]

Detailed Description

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The goal of this \[type of study: observational study \] is to \[compare Correlation between EEG data and postoperative delirium in elderly patients undergoing colorectal cancer radical surgery under preoperative frailty monitoring.\] in \[describe participant population selected 69 patients who underwent laparoscopic radical surgery for colorectal cancer on a selective basis\]. The main question\[s\] it aims to answer are:

• \[Is there any difference in the spectral range of EEG between POD patients and non POD patients\] Participants will \[Sedline EEG monitoring electrodes were placed 1cm above the eyebrows on both sides of the patient and at the temples on both sides, and were continuously monitored from the start of anesthesia in the operating room until the end of the surgery.Pay close attention to the vital signs and wait for the patient to fully recover and the vital signs to basically return to the preoperative level before returning to the ward.•Assessment of cognitive function using the Mini Mental State Scale (MMSE) 1 day before surgery and 7 days after surgery.•Preoperative assessment of frailty using the frailty screening scale.•Assess delirium using the ICU Patient Ambiguity Assessment Form (CAM-ICU) 1 day, 2 days, 3 days, and 7 days after surgery.\].

Conditions

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Postoperative Delirium Cognitive Function Abnormal PSI Frailty

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Non-delirious group

No postoperative delirium occurred

No interventions assigned to this group

Delirious group

Postoperative delirium occurs

delirium

Intervention Type BEHAVIORAL

Evaluation of delirium using the ICU Patient Ambiguity Assessment Form (CAM-ICU) 1 day, 2 days, 3 days, and 7 days after surgery

Interventions

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delirium

Evaluation of delirium using the ICU Patient Ambiguity Assessment Form (CAM-ICU) 1 day, 2 days, 3 days, and 7 days after surgery

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* ASA I-III
* The preoperative Frailty Scale (FRAIL) assessed frailty
* The patient or his/her family is informed about the study and signs an informed consent form

Exclusion Criteria

* Serious insufficiency of heart, liver, kidney and other functions
* Those with a history of psychiatric or neurological illness, long-term use of psychotropic drug
* History of cerebrovascular disease, brain trauma, or surgery
* The patient was allergic to coupler or unable to place electrodes on the head
* The patient was unable to complete the scale assessment as required.Patients with severe attention to hearing impairment were unable to complete the interview
* The patient was diagnosed with delirium before surgery
Minimum Eligible Age

65 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Zhuo Liu

OTHER_GOV

Sponsor Role lead

Responsible Party

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Zhuo Liu

Principal Investigator

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Qinshuang Liu, master

Role: STUDY_DIRECTOR

The First hosptial of Qinhuangdao

Zhaoheng Li, master

Role: STUDY_CHAIR

The First hosptial of Qinhuangdao

Locations

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The first hospital of Qinhuangdao

Qinhuangdao, Hebei, China

Site Status

Countries

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China

Other Identifiers

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lzh123456

Identifier Type: -

Identifier Source: org_study_id

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