Study on Biomarkers of Postoperative Delirium in Elderly Cardiac Surgery Patients

NCT ID: NCT06194474

Last Updated: 2024-01-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

24 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-09-05

Study Completion Date

2024-02-29

Brief Summary

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To evaluate the relationship between abnormal protein or metabolite expression levels in peripheral blood and postoperative delirium in elderly patients undergoing cardiac surgery.

Detailed Description

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Conditions

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Delirium

Study Design

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Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Study Groups

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Delirium Group

No interventions assigned to this group

No Delirium Group

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. patients between 55 and 80 years old,
2. American Society of Anesthesiologists (ASA) physical status of II-III and New York Heart Association grade of II-III.
3. The planned cardiac surgery.
4. Hospitalization duration not less than 5 days.
5. The anesthesia time will be no less than 2 hours.All patients had a normal ability to hear, read and cooperate with neuropsychological tests.

Exclusion Criteria

1. The pre-operative Montreal Cognitive Assessment (MoCA) score was less than 25,
2. Patients with dementia, history of neurological or psychiatric disease, hospital with anxiety depression scale (HADS) over eight points,
3. Currently use sedatives or antidepressants, Patients with substance dependence on drugs or alcohol.
4. Patients with liver and kidney dysfunction, patients with a history of cardiac surgery.
5. Admitted to the ICU for more than two days within the month preceding the current surgery,
6. Unable to cooperate with researcher's investigations.
Minimum Eligible Age

55 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Jining First People's Hospital

OTHER

Sponsor Role lead

Responsible Party

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Fuhui Yan

Study Director

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Fuhui Yan

Jining, Shandong, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Fuhui Yan

Role: CONTACT

155 8733 5175 ext. 86

Facility Contacts

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Fuhui Yan

Role: primary

15587335175

Other Identifiers

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JNFPH-2023-01

Identifier Type: -

Identifier Source: org_study_id

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