The Impact of Different Scanning Methods and Reconstruction Algorithms on CT Image Quality

NCT ID: NCT06142539

Last Updated: 2024-03-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-03-13

Study Completion Date

2025-05-31

Brief Summary

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Purpose: To evaluate the image quality of deep learning-based image reconstruction (DLIR) algorithm in unenhanced abdominal low-dose CT (LDCT).

Methods: CT images of a phantom were reconstructed with Hybrid iterative reconstruction and deep learning image reconstruction (DLIR). The noise power spectrum (NPS) and task transfer function (TTF) were measured. Two patient groups were included in this study: consecutive patients who underwent unenhanced abdominal standard-dose CT reconstructed with hybrid iterative reconstruction (SDCT group) and consecutive patients who underwent unenhanced abdominal LDCT reconstructed of HIR and DLIR (LDCT group). The CT values, standard deviation (SD), signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) of the hepatic parenchyma and paraspinal muscle and abdominal subcutaneous fat were evaluated. Radiologists assessed the subjective image quality and lesion diagnostic confidence using a 5-point Likert scale. Quantitative and qualitative parameters were compared between SDCT and LDCT groups.

Detailed Description

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Conditions

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CT Examination of the Abdomen

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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SDCT group

No interventions assigned to this group

LDCT group

CT Radiation Doses

Intervention Type RADIATION

Obtaining Low CT Radiation Doses by Adjusting Dose Levels

Interventions

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CT Radiation Doses

Obtaining Low CT Radiation Doses by Adjusting Dose Levels

Intervention Type RADIATION

Eligibility Criteria

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Inclusion Criteria

Abdominal CT examination

Exclusion Criteria

pregnancy and lactation for women unstable breath holding
Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Wei Li

OTHER

Sponsor Role lead

Responsible Party

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Wei Li

clinical professor

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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uCT960+

Shandong, Jinan Shandong, China

Site Status RECRUITING

Countries

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China

Central Contacts

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((Wei Li[Author])

Role: CONTACT

13869190655

Hui Qi

Role: CONTACT

13210607228

Facility Contacts

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((Wei Li[Author]), Dr

Role: primary

13869190655

References

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Qi H, Cui D, Xu S, Li W, Zeng Q. Image quality assessment of artificial intelligence iterative reconstruction for low dose unenhanced abdomen: comparison with hybrid iterative reconstruction. Abdom Radiol (NY). 2025 Jul;50(7):3353-3362. doi: 10.1007/s00261-024-04760-4. Epub 2024 Dec 21.

Reference Type DERIVED
PMID: 39707032 (View on PubMed)

Other Identifiers

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WLi

Identifier Type: -

Identifier Source: org_study_id

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