Computed Tomography Evaluation of Urinary Stones Densities Compared to in Vitro Analysis of Its Chemical Composition

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-03-30

Study Completion Date

2022-10-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The ability to predict stone composition, which influences patient treatment, depends on the accurate measurement of CT attenuation of stones. We will study the effects of stone composition, stone size, and scan collimation width on the measurement of attenuation in vitro.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Low Tube Voltage Computed Tomographic (CT) Urography Using Low Concentration Iodine Contrast Agent

NCT01855204

Exposure to Medical Diagnostic Radiation

UNKNOWN NA

Prospective Trial for Examining Hematuria Using Computed Tomography

NCT04077359

Urothelial Carcinoma Renal Cell Carcinoma Renal Cyst +1 more

COMPLETED NA

Impact of Acute Computed Tomography on Treatment Decisions and Time to Intervention in Renal Colic

NCT06535711

Kidney Stone

COMPLETED

Feasibility and Impact of a Decision Rule for Imaging of Emergency Department Patients With Suspected Kidney Stone

NCT01869647

Kidney Stones

COMPLETED NA

MR Urography vs CT Urography

NCT02606513

Neoplasms

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Recently, the use of noncontrast spiral computerized tomography (NCCT) has gained widespread acceptance in the evaluation of urinary stone patients. It has long been used clinically to evaluate the causes of radiolucent filling defects using Hounsfield units (HU) to distinguish calculi from tumor or blood clots, and to identify nonurologic causes of flank pain (Smith R etal ). Urinary stones have a significantly higher CT attenuation than the surrounding soft tissues and are virtually always visible on NCCT. Knowing the composition of a urinary calculus is frequently a key factor in determining its most appropriate management. Should the urine be alkalinized? Will the stone be amenable to extracorporeal shock wave lithotripsy (ESWL), or should ureteroscopy or percutaneous lithotripsy be attempted? Different techniques have been used to assist in determining the correct chemical composition of calculi. Urine pH, urinary crystals, prior stone history and the presence of urea-splitting organisms (Ramakumar S,etal). Several in vitro studies have suggested that NCCT can demonstrate measured differences in radiodensity among different urinary stones (Mitchenson HD etal,).With these clinical problems in mind, we sought to determine whether the composition of urinary calculi could be predicted by their CT characteristics in an attempt to find out the best technique for distinguishing the various stones compositions, provided that it is clinically practical and would not require repeated imaging of the patients.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Urinary Calculi

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Any Age will be included .
* Patient with suspected or known urinary stone disease.
* Eligible for doing NCCT.
* Giving written consent to participate

Exclusion Criteria

* Patient with classical NCCT contraindication like morbid obesity and pregnancy .
* Patients with urinary stones will be treated by ESWL
* Refusal participation .

Eligible Sex

ALL

Accepts Healthy Volunteers

No