Diagnosis of Acute Appendicitis: Low-dose Computed Tomography (CT) Versus Standard-dose CT
NCT ID: NCT00913380
Last Updated: 2011-09-12
Study Results
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View full resultsBasic Information
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COMPLETED
PHASE3
891 participants
INTERVENTIONAL
2009-09-30
2011-04-30
Brief Summary
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Detailed Description
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The estimated lifetime attributable risk of death from cancer due to the radiation exposure of a single abdomen CT study is 2-7/10,000 for average adults ranging 20-40 years in age.
The purpose of this study is to determine whether low-dose CT is not inferior to standard-dose CT in the negative appendectomy rate.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
DIAGNOSTIC
SINGLE
Study Groups
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Low-dose CT
Diagnostic CT
2 mSv in an average patient (Low-dose (1/4 to 1/5 of standard-dose))
Standard-dose CT
Diagnostic CT
8 mSv in an average patient (Standard-dose CT)
Interventions
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Diagnostic CT
2 mSv in an average patient (Low-dose (1/4 to 1/5 of standard-dose))
Diagnostic CT
8 mSv in an average patient (Standard-dose CT)
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Referred for abdomen CT from Emergency Department
Exclusion Criteria
* Intravenous contrast-enhancement is contraindicated
15 Years
44 Years
ALL
No
Sponsors
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GE Healthcare
INDUSTRY
National Research Foundation of Korea
OTHER
Seoul National University Bundang Hospital
OTHER
Responsible Party
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Kyoung Ho Lee
Dr.
Principal Investigators
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Kyoung Ho Lee, MD
Role: PRINCIPAL_INVESTIGATOR
Seoul National University Bundang Hospital
Kyuseok Kim, MD
Role: PRINCIPAL_INVESTIGATOR
Seoul National University Bundang Hospital
Locations
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Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, South Korea
Countries
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References
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Kim K, Kim YH, Kim SY, Kim S, Lee YJ, Kim KP, Lee HS, Ahn S, Kim T, Hwang SS, Song KJ, Kang SB, Kim DW, Park SH, Lee KH. Low-dose abdominal CT for evaluating suspected appendicitis. N Engl J Med. 2012 Apr 26;366(17):1596-605. doi: 10.1056/NEJMoa1110734.
Other Identifiers
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SNUBH-LDCTinAPPY
Identifier Type: -
Identifier Source: org_study_id
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