Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
292 participants
INTERVENTIONAL
2023-12-21
2025-12-31
Brief Summary
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1, Can low-dose contrast media paired with low-dose radiation CT of the abdomen provide acceptable diagnostic accuracy in acute appendicitis? 2. How much radiation dose can be saved by using low radiation dose abdominal CT in combination with low dose contrast media?
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
DIAGNOSTIC
NONE
Study Groups
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Double low-dose CT
Weight-adjusted low-dose contrast media paired with low-radiation dose abdomen CT
Weight-adjusted low-dose contrast media paired with low-radiation dose abdomen CT
The investigators are aiming for a 10% reduction in iodine dosage at 10 kVp reduction in CT radiation. Routine iodine dosing is 0.521 g I/kg at 120 kVp. Therefore, at 90 kVp, a 30% reduction in iodine dosing is expected, which is 0.365 g I/kg. At 100 kVp, the iodine dosage is reduced to 0.417 g I/kg, which is a 20% reduction. The kVp value is automatically selected by the CT device according to the body habitus, which is a clinical routine.
Interventions
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Weight-adjusted low-dose contrast media paired with low-radiation dose abdomen CT
The investigators are aiming for a 10% reduction in iodine dosage at 10 kVp reduction in CT radiation. Routine iodine dosing is 0.521 g I/kg at 120 kVp. Therefore, at 90 kVp, a 30% reduction in iodine dosing is expected, which is 0.365 g I/kg. At 100 kVp, the iodine dosage is reduced to 0.417 g I/kg, which is a 20% reduction. The kVp value is automatically selected by the CT device according to the body habitus, which is a clinical routine.
Eligibility Criteria
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Inclusion Criteria
* Patients scheduled for contrast-enhanced CT of the abdomen and pelvis for diagnosis of suspected acute appendicitis.
Exclusion Criteria
* Contraindications to contrast-enhanced CT (eGFR \< 30 mL/min/173 m\^2 or pregnant)
* BMI \>= 30.
19 Years
44 Years
ALL
No
Sponsors
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GE Healthcare
INDUSTRY
Bohyun Kim
OTHER
Responsible Party
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Bohyun Kim
Associate professor
Principal Investigators
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Bohyun Kim, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
Seoul St. Mary's Hospital
Locations
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Seoul St. Mary's Hospital
Seoul, , South Korea
Countries
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Central Contacts
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Facility Contacts
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Bohyun Kim
Role: primary
Other Identifiers
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DLD-001
Identifier Type: -
Identifier Source: org_study_id
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