Radiomic Modeling in Differentiating Uncomplicated From Complicated Acute Appendicitis

NCT ID: NCT05843630

Last Updated: 2023-05-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

250 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-01-03

Study Completion Date

2023-12-03

Brief Summary

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Non-operative management (NOM) with antibiotics may be a safe alternative to surgery for uncomplicated appendicitis, but preoperative differentiation between uncomplicated and complicated appendicitis is challenging. The study aimed to develop a clinical-radiomics nomogram to distinguish uncomplicated from complicated appendicitis.

Detailed Description

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Conditions

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Acute Appendicitis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Training cohort

Model construction based on training cohort

without

Intervention Type DIAGNOSTIC_TEST

without

Validation cohort 1

Model validation in an independent validation cohort 1

without

Intervention Type DIAGNOSTIC_TEST

without

Validation cohort 2

Model validation in an independent validation cohort 2

without

Intervention Type DIAGNOSTIC_TEST

without

Interventions

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without

without

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Pathologically diagnosed as acute appendicitis after appendectomy between January 2021 and December 2022.

Exclusion Criteria

* age less than 18 years (no upper age limit);
* without CT examination within a week before surgery;
* difficult to outline the contours of the appendix due to inflammatory exudate;
* lack of clinical information.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Kecheng Zhang

OTHER

Sponsor Role lead

Responsible Party

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Kecheng Zhang

Department of General Surgery, Chinese PLA General Hospital First Medical Center

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Kecheng Zhang

Role: PRINCIPAL_INVESTIGATOR

Senior Department of General Surgery, Chinese PLA General Hospital

Locations

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Chinese PLA General Hospital First Medical Center

Beijing, , China

Site Status RECRUITING

Countries

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China

Central Contacts

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LI LI

Role: CONTACT

13210613213

Facility Contacts

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Kecheng Zhang

Role: primary

Other Identifiers

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PLAGH202304

Identifier Type: -

Identifier Source: org_study_id

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