Non Contrast CT in Acute Appendicitis

NCT ID: NCT05815446

Last Updated: 2023-04-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

78 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-04-20

Study Completion Date

2023-12-30

Brief Summary

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To evaluate Diagnostic accuracy of Non-contrast CT in correlation with ultrasound in diagnosis of acute appendicitis in adults

Detailed Description

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Acute appendicitis is a prevalent cause of abdominal pain, with an estimated lifetime risk of 7 to 9%.\[1\] Diagnosing appendicitis on CT has a sensitivity and specificity of 87% and 76%, respectively. Classically, diagnosis of acute appendicitis is by identifying an enlarged appendix (greater than 6 mm in diameter) .

Some studies suggest using a cut-off value of over 7 mm to improve the prognostic capability of CT.

On the other hand, appendicitis is regularly diagnosed using radiology studies. In fact, imaging is often the deciding factor between operative and non-operative management. Though the diagnosis can be clinical following a thorough history and physical, imaging is regularly employed to confirm the diagnosis in question. The most commonly used radiographic study is the CT scan, given its speed, sensitivity, and specificity. US is also relatively useful modality to diagnose acute appendicitis, it has its limitations. Ultrasound is highly operator dependent and tends to work best on individuals with less fat and muscle content in their abdomen (i.e., children). Currently, the negative appendectomy is less than 12% in men but can be up to 33% in women; accurate imaging studies could reduce the number of unnecessary surgeries performed on patients. It is, therefore, essential to know which study will provide the clinician with the most accurate information for their specific clinical scenario.

Conditions

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Acute Appendicitis

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Interventions

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CT

NON CONTASR COMPUTED TOMOGRAPHY

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Adult patient (male or female) with clinical suspicion of acute appendicitis .

Exclusion Criteria

* pregnant ladies and patients with history of appendectomy
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Shaimaa Omar Mohamed Ali

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

References

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Cohen CI. A case report: periodontal surgery in Parkinsonism utilizing intravenous sedation. N Y State Dent J. 1978 Jan;44(1):19. No abstract available.

Reference Type BACKGROUND
PMID: 271274 (View on PubMed)

Drazen JM. Asthma therapy with agents preventing leukotriene synthesis or action. Proc Assoc Am Physicians. 1999 Nov-Dec;111(6):547-59. doi: 10.1046/j.1525-1381.1999.t01-1-99242.x.

Reference Type BACKGROUND
PMID: 10591083 (View on PubMed)

Other Identifiers

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CT in acute appendicitis

Identifier Type: -

Identifier Source: org_study_id

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