Radiological Findings in Primary Intestinal Ischaemia

NCT ID: NCT04361110

Last Updated: 2020-04-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

130 participants

Study Classification

OBSERVATIONAL

Study Start Date

2006-01-01

Study Completion Date

2009-12-31

Brief Summary

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To investigate which findings on a non-specific CT scan that predict acute primary intestinal ischaemia.

Detailed Description

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48 patients with primary intestinal ischemia admitted in 4 consecutive years (2006-2009) in Department of Gastrointestinal Surgery, Aalborg University Hospital. Control group consists of 82 patients operated in the same department and in the same time range.

Abdominal CT scans are described with respect to intestinal diameter, changes in intestinal wall, extra intestinal changes and vessel pathology.

Conditions

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Acute Intestinal Ischemia

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Acute intestinal ischaemia

Abdominal CT scan within 48 hours preoperative.

Computerized tomography scan of the abdomen

Intervention Type RADIATION

Non-specific abdominal ct´s with different phases and contrast +/-.

Controls

Abdominal CT scan within 48 hours preoperative.

Computerized tomography scan of the abdomen

Intervention Type RADIATION

Non-specific abdominal ct´s with different phases and contrast +/-.

Interventions

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Computerized tomography scan of the abdomen

Non-specific abdominal ct´s with different phases and contrast +/-.

Intervention Type RADIATION

Eligibility Criteria

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Inclusion Criteria

* Primary acute intestinal ischaemia in an abdominal operation.
* CT-scan within 48 hours preoperative.

Exclusion Criteria

* Secondary intestinal ischaemia
* Intestinal ischaemia isolated intestinal mucosa.
* No CT-scan within 48 hours preoperative
Maximum Eligible Age

120 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Aalborg University Hospital

OTHER

Sponsor Role lead

Responsible Party

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David Straarup

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

References

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Menke J. Diagnostic accuracy of multidetector CT in acute mesenteric ischemia: systematic review and meta-analysis. Radiology. 2010 Jul;256(1):93-101. doi: 10.1148/radiol.10091938.

Reference Type BACKGROUND
PMID: 20574087 (View on PubMed)

Karkkainen JM, Acosta S. Acute mesenteric ischemia (part I) - Incidence, etiologies, and how to improve early diagnosis. Best Pract Res Clin Gastroenterol. 2017 Feb;31(1):15-25. doi: 10.1016/j.bpg.2016.10.018. Epub 2017 Jan 4.

Reference Type BACKGROUND
PMID: 28395784 (View on PubMed)

Tilsed JV, Casamassima A, Kurihara H, Mariani D, Martinez I, Pereira J, Ponchietti L, Shamiyeh A, Al-Ayoubi F, Barco LA, Ceolin M, D'Almeida AJ, Hilario S, Olavarria AL, Ozmen MM, Pinheiro LF, Poeze M, Triantos G, Fuentes FT, Sierra SU, Soreide K, Yanar H. ESTES guidelines: acute mesenteric ischaemia. Eur J Trauma Emerg Surg. 2016 Apr;42(2):253-70. doi: 10.1007/s00068-016-0634-0.

Reference Type BACKGROUND
PMID: 26820988 (View on PubMed)

Cudnik MT, Darbha S, Jones J, Macedo J, Stockton SW, Hiestand BC. The diagnosis of acute mesenteric ischemia: A systematic review and meta-analysis. Acad Emerg Med. 2013 Nov;20(11):1087-100. doi: 10.1111/acem.12254.

Reference Type BACKGROUND
PMID: 24238311 (View on PubMed)

Aschoff AJ, Stuber G, Becker BW, Hoffmann MH, Schmitz BL, Schelzig H, Jaeckle T. Evaluation of acute mesenteric ischemia: accuracy of biphasic mesenteric multi-detector CT angiography. Abdom Imaging. 2009 May-Jun;34(3):345-57. doi: 10.1007/s00261-008-9392-8.

Reference Type BACKGROUND
PMID: 18425546 (View on PubMed)

Straarup D, Gotschalck KA, Mikalone R, Thorlacius-Ussing O. Preoperative findings on non-specific CT in patients with primary acute intestinal ischemia: a case-control study. Eur J Trauma Emerg Surg. 2022 Aug;48(4):3025-3032. doi: 10.1007/s00068-021-01741-w. Epub 2021 Jul 3.

Reference Type DERIVED
PMID: 34216221 (View on PubMed)

Other Identifiers

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Acute intestinal ischaemia

Identifier Type: -

Identifier Source: org_study_id

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