Negative Oral Contrast Agents Utilization in PET/CT Studies

NCT ID: NCT04577586

Last Updated: 2020-10-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-09-01

Study Completion Date

2021-04-01

Brief Summary

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To compare the performance of different negative oral contrast agents in bowel distension in patient referred for PET/CT studies for various causes aiming for identification of ideal oral contrast agent(OCA).

Detailed Description

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Evaluation of gastrointestinal pathology depends on adequate bowel distention, which optimizes resolution of the bowel wall and contents. Traditionally, high-attenuation oral Contrast material in the form of iodine solutions or barium suspensions has been used to obtain bowel distension in MDCT examinations

Traditional high-contrast oral agents like iodine solutions, and barium suspensions which due to overcorrection problems in PET-CT interpretation lowers the accuracy of diagnosis. Negative oral contrast agents like water, air, fat containing agents used with 12.5% corn oil and polyethylene glycol has been used in radiological studies. Milk with 4% fat content has also been tested out in radiological studies and found to be effective. As it is more easily available, palatable, and acceptable especially, by children it needed to be tested in the visualization of the GIT in the PET-CT studies compared to other negative contrast agents.

Conditions

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PET/CT Oral Contrast

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Water

Patients who ingested only water as an oral contrast

oral contrast

Intervention Type OTHER

negative oral contrast utilization in PET/CT studies

Milk

Patients who ingested milk as an oral contrast

oral contrast

Intervention Type OTHER

negative oral contrast utilization in PET/CT studies

Mannitol

Patients who ingested mannitol as an oral contrast

oral contrast

Intervention Type OTHER

negative oral contrast utilization in PET/CT studies

Interventions

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oral contrast

negative oral contrast utilization in PET/CT studies

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* all patients referred to our unit for PET/CT study for various causes

Exclusion Criteria

* Patients with GIT disease.
* Pregnancy and lactation.
* Severely ill patients.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Nahla Mostafa Mahmoud Bashank

PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Faculty of Medicine

Asyut, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Nahla mostafa Bashank, Phd

Role: CONTACT

01009466255

Facility Contacts

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Nahla Bashank, MD

Role: primary

01009466255

References

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Meyer SA, Gawde S. Utility of negative oral contrast (milk with 4% fat) in PET-CT studies. Indian J Nucl Med. 2012 Jul;27(3):151-5. doi: 10.4103/0972-3919.112719.

Reference Type BACKGROUND
PMID: 23919067 (View on PubMed)

Koo CW, Shah-Patel LR, Baer JW, Frager DH. Cost-effectiveness and patient tolerance of low-attenuation oral contrast material: milk versus VoLumen. AJR Am J Roentgenol. 2008 May;190(5):1307-13. doi: 10.2214/AJR.07.3193.

Reference Type BACKGROUND
PMID: 18430848 (View on PubMed)

Other Identifiers

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Negative oral contrast PET/CT

Identifier Type: -

Identifier Source: org_study_id

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