Influence of Patient Position on Attenuation Artifacts Observed in D-SPECT Camera Myocardial Tomoscintigraphy
NCT ID: NCT02872545
Last Updated: 2016-08-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
80 participants
INTERVENTIONAL
2016-06-30
2017-06-30
Brief Summary
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The hypothesis is that the percentage of myocardial segments with attenuation is significantly lower when acquisitions are made in forward tilted position (biker position).
The secondary purpose is to restrict this analysis to 3 cardiac regions most subject to attenuation artifacts (anterior, apical and inferobasal regions).
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Detailed Description
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A common problem is attenuation artifacts that are due to tissue interposition attenuating radiation from some cardiac regions. These artifacts originate activity decreasing and thus perfusion abnormalities potentially in all walls of left ventricle, especially the inferior wall in men (attenuation by sub-diaphragmatic organs) and the anterior wall in women (attenuation by mammary glands). These artifacts are observed in rest and stress acquisitions and can lead to a wrong diagnosis of infarction.
Attenuation artifacts can be identified with analysis of contraction kinetics with "gated-SPECT" (normal kinetics and thus discordant with aspect of infarction). With D-SPECT camera some artifacts can be prevented with a 30-35° forward tilted position of acquisition. This position, also called biker position, can take cardiac area away from sub-diaphragmatic structures. It can also reduce the distance between heart and detection surface of camera and limit respiratory movements of thoracic wall.
In this study, patients with abnormal results at stress myocardial perfusion tomoscintigraphy will undergo a rest tomoscintigraphy. Acquisition will be done in forward tilted position and in one of 2 other positions: dorsal decubitus or semi sitting.
Conditions
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Study Design
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NON_RANDOMIZED
CROSSOVER
DIAGNOSTIC
NONE
Study Groups
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forward tilted
Patients with abnormal results at stress myocardial perfusion tomoscintigraphy will undergo a rest tomoscintigraphy. Acquisition will be done in forward tilted position
Rest tomoscintigraphy in forward tilted
Rest tomoscintigraphy in forward tilted position
Rest tomoscintigraphy in semi sitting position
Rest tomoscintigraphy in forward tilted position, followed by a second rest tomoscintigraphy in semi sitting position, after max 30 min
Rest tomoscintigraphy in dorsal decubitus position
Rest tomoscintigraphy in forward tilted position, followed by a second rest tomoscintigraphy in semi sitting position, after max 30 min
semi sitting
Patients with abnormal results at stress myocardial perfusion tomoscintigraphy will undergo a rest tomoscintigraphy. Acquisition will be done in semi sitting
Rest tomoscintigraphy in forward tilted
Rest tomoscintigraphy in forward tilted position
Rest tomoscintigraphy in semi sitting position
Rest tomoscintigraphy in forward tilted position, followed by a second rest tomoscintigraphy in semi sitting position, after max 30 min
dorsal decubitus
Patients with abnormal results at stress myocardial perfusion tomoscintigraphy will undergo a rest tomoscintigraphy. Acquisition will be done in dorsal decubitus
Rest tomoscintigraphy in forward tilted
Rest tomoscintigraphy in forward tilted position
Rest tomoscintigraphy in dorsal decubitus position
Rest tomoscintigraphy in forward tilted position, followed by a second rest tomoscintigraphy in semi sitting position, after max 30 min
Interventions
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Rest tomoscintigraphy in forward tilted
Rest tomoscintigraphy in forward tilted position
Rest tomoscintigraphy in semi sitting position
Rest tomoscintigraphy in forward tilted position, followed by a second rest tomoscintigraphy in semi sitting position, after max 30 min
Rest tomoscintigraphy in dorsal decubitus position
Rest tomoscintigraphy in forward tilted position, followed by a second rest tomoscintigraphy in semi sitting position, after max 30 min
Eligibility Criteria
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Inclusion Criteria
* Signed informed consent
* Previous clinical examination authorizing patient to undergo tomoscintigraphy
* Patient with abnormal results of stress tomoscintigraphy and needing a rest tomoscintigraphy
* Patient with sinus and regular cardiac rhythm
* Patient with stable clinical status (without signs of unstable cardiac or coronary failure, without uncontrolled hypertension under treatment)
Exclusion Criteria
* Evolutive pregnancy
* Breastfeeding patient
* Contraindication to tomoscintigraphy
* Patient with history of hypersensibility to tomography radiotracer STAMICIS® or one of components
* Patient in life-and-death emergency
* Patient with history of disorders possibly interfering with contractility
* Patient with normal results of stress tomoscintigraphy
* Person under legal protection or incapable to consent
* Person deprived of liberty by judicial or administrative decision
18 Years
ALL
No
Sponsors
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Central Hospital, Nancy, France
OTHER
Responsible Party
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Principal Investigators
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Mathieu PERRIN, Dr
Role: PRINCIPAL_INVESTIGATOR
Service de Médecine Nucléaire - CHRU de Nancy-Brabois - Vandoeuvre Lès Nancy
Locations
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Service de Médecine Nucléaire - CHRU de Nancy-Brabois
Vandœuvre-lès-Nancy, , France
Countries
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Central Contacts
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Other Identifiers
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2016-A00378-43
Identifier Type: -
Identifier Source: org_study_id
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