Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
40 participants
OBSERVATIONAL
2017-10-01
2019-11-30
Brief Summary
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Detailed Description
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Since X-ray image has a discrepancy with clinical findings, the therapeutic modalities tend to depend on the clinical symptoms, rather than the objective imaging findings.
MRI is a non-invasive and a very sensitive tool in detecting the early bony change such as bone marrow oedema, but it has some limitation in that it may have false positive or false negative results in the detection of the patella-femoral (PF) lesions. Bone scintigraphy is relatively sensitive because it reflects the early physiological changes of joints. But its image is planar that it cannot give enough information for the anatomic localization, and the image is overlapped.
To compensate for the defects of these imaging methods, bone single photon emission computed tomography (SPECT) has emerged as useful imaging tools in the diagnosis of OA.
Based upon the fact that subchondral bony changes precede joint space narrowing in OA, bone SPECT seems to be a very useful tool in early OA, reflecting the early bony changes.
The use of SPECT/CT offers the benefit of combined anatomical, mechanical (CT) and functional imaging (SPECT), which represents a relevant improvement in preoperative diagnosis and follow-up after procedures.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Interventions
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SPECT/CT
Combined single photon emission computerized tomography and conventional computerized tomography (SPECT/CT) is a hybrid imaging modality, which combines a 3D bone scintigraphy (SPECT) and a conventional CT into one imaging procedure. The use of SPECT/CT offers the benefit of combined anatomical, mechanical (CT) and functional imaging (SPECT)
Eligibility Criteria
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Inclusion Criteria
* Clinically diagnosed osteoarthritis before treatment.
* Patient with refractory active osteoarthritis (not responding to treatment).
* Ability to sleep in fixed position for about 25 minutes
* Ability to provide informed consent.
Exclusion Criteria
* patient with other disease in joints:
* Avascular necrosis
* Stress fracture
* Neuropathic pain
30 Years
75 Years
ALL
No
Sponsors
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Assiut University
OTHER
Responsible Party
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Fatma El-Zahraa Mostafa Mahmoud
resident physicians
Central Contacts
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Other Identifiers
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SPECT/CT in osteoarthritis
Identifier Type: -
Identifier Source: org_study_id