Radiation Dose From Computed Tomography Before and After Implementation of a High Pitch Dual Spiral Technique

NCT ID: NCT01111760

Last Updated: 2013-04-05

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 334 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2010-05-31
• Study Completion Date: 2013-02-28

Brief Summary

The purpose of this study is to compare the radiation exposure of a variety of chest CT examinations performed on the current state of the art CT scanners (64 slice, dual source CT scanner) with the radiation exposure for identical chest CT examinations performed on the Siemens Flash CT scanner (high pitch dual source spiral technique).

Detailed Description

Computed tomography has emerged as the "gold standard" for the diagnosis of a broad range of medical diagnoses. For cardiac imaging alone, the installation of CT scanners in US cardiology practices alone has tripled over the past 2 years. Patients who undergo cardiac CTA (computed tomography angiography) may be subjected to relatively high doses of ionizing radiation (ie. 4 times annual background radiation) during the diagnosis and management of coronary artery disease. Current radiation doses for cardiac CT examinations are comparable to the effective doses for patients undergoing nuclear stress tests or cardiac catheterization (ie. approximately 10-15 milliSieverts). In addition, non cardiac CT protocols, such as chest CT examinations for the evaluation of pulmonary arteries, thoracic and abdominal aorta, and lung nodules, are associated with significant radiation exposure. Many patients undergo repeated CT examinations over several years for such pathology. There is a growing public concern regarding the cancer risk associated with such radiation.

Recent major technological advances have been made with the advent of newer generation CT scanners which allow significant radiation dose reduction. One such scanner, the dual source CT, is a new high pitch dual source spiral technique that offers the ability to image a patient's chest with ECG gated imaging protocols within a single second. These technological advances allow significant radiation dose savings, often resulting in effective radiation doses of less than one millisievert (mSv).

Conditions

Atherosclerosis of Coronary Artery; Cardiovascular Disease; Pulmonary Embolism; Aortic Aneurysm Without Mention of Rupture Nos

Study Design

• Observational Model Type: CASE_ONLY

Eligibility Criteria

Inclusion Criteria

• All patients who undergo chest CT examinations (including cardiac CTA, and non cardiac CT examinations including pulmonary embolism, lung nodule and aortic pathology protocols)

• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Michael Gallagher

OTHER

Sponsor Role: lead

Responsible Party

Michael Gallagher

Cardiologist

Responsibility Role: SPONSOR_INVESTIGATOR

Principal Investigators

Michael Gallagher, MD

Role: PRINCIPAL_INVESTIGATOR

William Beaumont Hospitals

Gilbert Raff, MD

Role: STUDY_DIRECTOR

William Beaumont Hospitals

Locations

William Beaumont Hospital-Royal Oak

Royal Oak, Michigan, United States

Countries

United States

Other Identifiers

HIC 2010-082

Identifier Type: -

Identifier Source: org_study_id