Computed Tomography Versus Exercise Testing in Suspected Coronary Artery Disease
NCT ID: NCT01393028
Last Updated: 2014-11-13
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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TERMINATED
NA
350 participants
INTERVENTIONAL
2011-07-31
2014-08-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
DIAGNOSTIC
NONE
Study Groups
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Cardiac CT
Cardiac CT (CT calcium and/or CT angiography), followed by stress testing, invasive angiography or neither depending on the CT scan result
Cardiac CT
Cardiac CT: calcium scan and CT coronary angiography
Standard care
Standard diagnostic management, including stress testing and/or invasive angiography
Standard care
Standard care according to international guidelines
Interventions
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Cardiac CT
Cardiac CT: calcium scan and CT coronary angiography
Standard care
Standard care according to international guidelines
Eligibility Criteria
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Inclusion Criteria
* Stable symptoms of chest pain or dyspnea potentially caused by obstructive CAD.
Exclusion Criteria
* Non-revascularized angiographic obstructive coronary artery disease (\>50% diameter reduction).
* Normal invasive coronary angiography or stress imaging less than 1 years ago.
* Inability or unwillingness to provide informed consent.
18 Years
ALL
No
Sponsors
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Erasmus Medical Center
OTHER
Responsible Party
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Koen Nieman
Dr K Nieman
Locations
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MC Haaglanden
Leidschendam, , Netherlands
Erasmus MC
Rotterdam, , Netherlands
Havenziekenhuis
Rotterdam, , Netherlands
Maasstadziekenhuis
Rotterdam, , Netherlands
Countries
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References
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Lubbers M, Coenen A, Bruning T, Galema T, Akkerhuis J, Krenning B, Musters P, Ouhlous M, Liem A, Niezen A, Dedic A, van Domburg R, Hunink M, Nieman K. Sex Differences in the Performance of Cardiac Computed Tomography Compared With Functional Testing in Evaluating Stable Chest Pain: Subanalysis of the Multicenter, Randomized CRESCENT Trial (Calcium Imaging and Selective CT Angiography in Comparison to Functional Testing for Suspected Coronary Artery Disease). Circ Cardiovasc Imaging. 2017 Feb;10(2):e005295. doi: 10.1161/CIRCIMAGING.116.005295.
Other Identifiers
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CRESCENT-11
Identifier Type: -
Identifier Source: org_study_id