Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
121 participants
OBSERVATIONAL
2023-03-20
2025-05-20
Brief Summary
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\* This research will provide new information on how sweet taste perception is regulated.
* The hypothesis: Greater dietary consumption of sugar and sweet foods is associated with reduced expression of the sweet taste receptors.
* The results of this study could help to identify pathways to help modify sweet taste perception by uncovering this mechanism.
Participants will sample solutions prepared with sweet ingredients, provide salivary DNA, and collect fungiform papillae. This will allow researchers and investigators to compare the relationship between the sweetness of stimuli, genetic differences in sweet taste receptors, and expression levels of sweet taste receptor genes.
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Detailed Description
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Conditions
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Study Design
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OTHER
OTHER
Eligibility Criteria
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Inclusion Criteria
2. have no tongue or cheek piercings,
3. not a user of tobacco products or electronic cigarettes (within the last year),
4. no known defects in taste or smell,
5. not pregnant or breastfeeding,
6. no history of chronic pain in the mouth,
7. not taking any prescription pain medication,
8. not taking any blood thinners,
9. no history of cancer or cancer treatment,
10. not diabetic or restricting intake of sugars for medical reasons, under the direction of a physician or healthcare provider
11. willing to undergo the Fungiform Papillae biopsy procedure
12. willing to provide salivary DNA
13. Not currently experiencing any COVID-19 symptoms
14. Not recently diagnosed (in the last 30 days) with COVID-19
15. No history of high blood pressure
Exclusion Criteria
18 Years
45 Years
ALL
No
Sponsors
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National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH
University of Massachusetts, Amherst
OTHER
Responsible Party
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Locations
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University of Massachusetts
Amherst, Massachusetts, United States
Countries
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Other Identifiers
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2587
Identifier Type: -
Identifier Source: org_study_id
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