Short-term Sleep Restriction on Taste Preference and Perception

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-09-01

Study Completion Date

2023-02-28

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The study aims is to investigate the effects of sleep restriction on sweet and fat taste perception and preference in both fasted and fed states. This is a randomised crossover trial with sleep restriction (4 hours per night for 2 nights) and normal sleep (at least 8 hours sleep for 2 nights) conditions, with a four-week washout period between conditions.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Olfactory and Taste Changes During Fasting Mimicking Diet (FMD)

NCT04529161

Diet, Healthy Obesity Olfaction Disorders

COMPLETED NA

Umami Taste Intensity and ad Libitum Meal Intake

NCT07059117

Taste Sensitivity Umami Taste Perception Food Intake Regulation +2 more

COMPLETED NA

The Effect of Dietary Sugar Consumption on Sweet Taste Perception

NCT02090478

Sweet Taste Perception

COMPLETED NA

Repeated Exposure to Umami Taste on Taste Perception, Hedonics, and Satiety

NCT03010930

Umami Taste Perception

COMPLETED NA

Sorting of Oral Sensations

NCT02390180

Taste Qualities Primary Tastes

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Sleep restriction has been found to dysregulate appetite regulation, leading to an increased food intake, particularly of foods high in sugar and fat. It is unclear why sleep restriction leads to increased fat and sugar intake, but emerging evidence suggests that taste preference and perception may be influenced by the lack of sleep.

Sleep restriction leads to increased preference for sucrose. However it is unclear whether sleep restriction also alters perception of sweetness, or whether it affects preference or perception of dietary fat. It is also unclear, whether any changes in sweet and fat preference and perception due to sleep restriction differ between the fasted and fed states.

This study is a randomised crossover trial where each participant will undertake two conditions (sleep restriction and normal sleep) in a randomised order. In the sleep restriction condition, participants will be asked to restrict their sleep duration to a maximum of four hours per night for two nights, and in the normal sleep group they will be asked to sleep for at least eight hours per night for two nights. There will a 4-week wash-out period between conditions. After each condition (2 nights of normal sleep or 2 nights of sleep restriction), particpants asked to arrive in a fasted state for the assessments. They will initially undertake the Control of Eating Questionnaire (COEQ) and the Leeds Food Preference Questionnaire (LFPQ). Participants will then undertake the sweet and fat taste perception and preference tests (described below). Following this, all participants will be provided with a standardized breakfast meal, and 60 minutes later, the LFPQ and taste preference and perception tests will be repeated in fed state.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Sleep Restriction Normal Sleep

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

A randomised crossover trial with one group undergoing two conditions- a sleep restriction condition and a normal sleep condition.

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Sleep Restriction Condition

Participants will be asked to restrict their sleep duration to a maximum of four hours per night (3 am to 7 am) for the two nights prior to the measurement day.

Group Type EXPERIMENTAL

Sleep Restriction and Normal Sleep

Intervention Type BEHAVIORAL

The intervention will consist of either sleep restriction (4 hours per night, 3 am to 7 am) or normal sleep (8 hours per night 11 pm to 7 am) for a duration of two nights.

Normal Sleep Condition

Participants will be asked to sleep for at least eight hours per night (11 pm to 7 am) for two nights prior to the measurement day.

Group Type EXPERIMENTAL

Sleep Restriction and Normal Sleep

Intervention Type BEHAVIORAL

The intervention will consist of either sleep restriction (4 hours per night, 3 am to 7 am) or normal sleep (8 hours per night 11 pm to 7 am) for a duration of two nights.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Sleep Restriction and Normal Sleep

The intervention will consist of either sleep restriction (4 hours per night, 3 am to 7 am) or normal sleep (8 hours per night 11 pm to 7 am) for a duration of two nights.

Intervention Type BEHAVIORAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* 18 years and above
* Self Reported sleep of \>7 hours a night

Exclusion Criteria

* Dairy allergy
* Presence of any serious medical conditions which might influence sleep i.e cardiovascular diseases, diabetes, cancer, respiratory disease, other than mild asthma)
* History of bariatric surgery
* Taking any kind of medication which might affect regular sleep
* Taking any type of medication which might affect appetite
* Participating in any kind of dietary and/or weight loss programs
* Taking antidepressants
* Substance or alcohol abuse
* Shift work
* Currently having to wake up at night to care for another person
* Suffering from and/or receiving treatment for mental health conditions or sleep apnoea.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes