Alteration of Sweet Taste Perception After Reduction of Sweet Food and Beverage Consumption.

NCT ID: NCT06678386

Last Updated: 2024-11-07

Basic Information

• Recruitment Status: ENROLLING_BY_INVITATION
• Clinical Phase: NA
• Total Enrollment: 58 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2024-10-01
• Study Completion Date: 2025-07-31

Brief Summary

The goal of this clinical trial is to determine whether reducing sugar intake by 50% for 12 weeks can change sweet taste perception in healthy adults and its consequences. The main questions it aims to answer are:

• Does sweet intensity change after reducing daily sugar intake by 50% for 12 weeks?
• How does sweet intensity change after completing dietary modification for 8 weeks?
• Does individual daily sugar intake change after completing dietary modification for 8 weeks?

Researchers will compare reducing daily sugar intake by 50% for 12 weeks to an unmodified diet to see if sugar reduction can change sweet intensity.

Participants will:

• Reduce daily sugar intake by 50% or maintain an unmodified diet for 12 weeks.
• Visit the clinic three times for anthropometric measurements, sweet perception tests, and to complete questionnaires.
• Keep a diet record for a total of 15 days during the research period.

Conditions

Health-Related Behavior

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: PREVENTION
• Blinding Strategy: TRIPLE

Study Groups

50% sugar reduction

Participants were advised by a dietitian to reduce their daily caloric intake from sugars by 50% for 12 weeks.

Group Type: EXPERIMENTAL

50% sugar reduction

Intervention Type: BEHAVIORAL

Participants were advised by a dietitian to reduce their daily caloric intake from sugars by 50% for 12 weeks.

unmodified diet

Participants maintained an unmodified diet.

Group Type: NO_INTERVENTION

No interventions assigned to this group

Interventions

50% sugar reduction

Participants were advised by a dietitian to reduce their daily caloric intake from sugars by 50% for 12 weeks.

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• People with a fasting blood sugar level below 126 mg/dL or an HbA1C below 6.5% in the past 6 months, who are not currently being treated for diabetes.
• People who score 10 or more points on the sweet food consumption behavior questionnaire.
• People who are able to communicate in the Thai language.
• People who are able to chat and use video calls via the Line application.
• People who agree to modify their diet and beverages according to the recommendations of a dietitian.
• People who agree to undergo sweet taste testing, complete a food record, and fill out a questionnaire.

Exclusion Criteria

• People with uncontrolled chronic conditions who have had changes in their treatment within the past 3 months.
• People with a history of severe illness in the past 6 months.
• People who regularly use medication, excluding contraceptives and vitamins.
• Pregnant women.
• People who have experienced a weight change of at least 10% over the past 3 months.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 59 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Mahidol University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Faculty of Medicine Siriraj Hospital, Mahidol University

Bangkoknoi, Bangkok, Thailand

Countries

Thailand

Other Identifiers

233/2567 (IRB1)

Identifier Type: -

Identifier Source: org_study_id