Investigating the Effects of Krill Oil and Krill Protein on Post-exercise Muscle Protein Metabolism

NCT ID: NCT05774444

Last Updated: 2025-03-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

48 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-05-01

Study Completion Date

2025-05-25

Brief Summary

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The aim of the current study is to find out if krill oil can increase muscle building processes in response to resistance (weightlifting) type exercise. Others aim are to determine the effects of krill protein, and the interaction of krill oil and protein, on muscle building processes in response to resistance (weightlifting) type exercise.

Detailed Description

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Conditions

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Hypertrophy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Parallel 2x2 factorial design
Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors
All supplements with be colour and flavour matched

Study Groups

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Vegetable oil + Carbohydrate

The vegetable oil will be a placebo control for the Krill oil (4g/day). The carbohydrate will be a placebo control for the Krill protein (20g)

Group Type PLACEBO_COMPARATOR

Vegetable oil

Intervention Type DIETARY_SUPPLEMENT

This will be the control against the Krill oil

Carbohydrate

Intervention Type DIETARY_SUPPLEMENT

This will be the control for the Krill protein

Vegetable oil + Krill protein

The vegetable oil will be a placebo control for the Krill oil (4g/day). Krill protein will be our active intervention (20g)

Group Type EXPERIMENTAL

Krill protein

Intervention Type DIETARY_SUPPLEMENT

Krill protein will be given to the participant following a resistance exercise bout.

Vegetable oil

Intervention Type DIETARY_SUPPLEMENT

This will be the control against the Krill oil

Krill oil + Carbohydrate

The Krill oil will be the active supplement for the intervention (4g/day). The carbohydrate will be a placebo control for the Krill protein (20g)

Group Type EXPERIMENTAL

Krill oil

Intervention Type DIETARY_SUPPLEMENT

Krill oil will be supplemented to see if they can gain strength and/or muscle mass following supplementation.

Carbohydrate

Intervention Type DIETARY_SUPPLEMENT

This will be the control for the Krill protein

Krill oil + Krill protein

Both the Krill oil (4g/day) and the Krill protein will be the active intervention supplements (20g)

Group Type EXPERIMENTAL

Krill oil

Intervention Type DIETARY_SUPPLEMENT

Krill oil will be supplemented to see if they can gain strength and/or muscle mass following supplementation.

Krill protein

Intervention Type DIETARY_SUPPLEMENT

Krill protein will be given to the participant following a resistance exercise bout.

Interventions

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Krill oil

Krill oil will be supplemented to see if they can gain strength and/or muscle mass following supplementation.

Intervention Type DIETARY_SUPPLEMENT

Krill protein

Krill protein will be given to the participant following a resistance exercise bout.

Intervention Type DIETARY_SUPPLEMENT

Vegetable oil

This will be the control against the Krill oil

Intervention Type DIETARY_SUPPLEMENT

Carbohydrate

This will be the control for the Krill protein

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Be 60 years old or older
* Have a BMI of less than 35kg/m2
* Be participating in structured exercise for less than 2h per week

Exclusion Criteria

* Diabetes
* Severe cardiovascular disease
* Seizure disorders,
* Uncontrolled hypertension (\>150/90mmHg at baseline measurement)
* Cancer or cancer that has been in remission \<5 years
* Ambulatory impairments which would limit ability to perform assessments of muscle function
* Dementia
* Taking medication known to affect muscle (e.g., steroids)
* Have an implanted electronic device (e.g., pacemaker/defibrillator/insulin pump),
* Anticoagulant therapy
* Allergies to seafood
* Regular consumption of more than 1 portion of oily fish per week.
Minimum Eligible Age

60 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Aker BioMarine

UNKNOWN

Sponsor Role collaborator

University of Glasgow

OTHER

Sponsor Role lead

Responsible Party

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Stuart Gray

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Stuart Robert Gray

Glasgow, , United Kingdom

Site Status RECRUITING

Countries

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United Kingdom

Facility Contacts

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Stuart R Gray

Role: primary

01413302569

Role: backup

01413302569 ext. Gray

Other Identifiers

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KIPLING

Identifier Type: -

Identifier Source: org_study_id

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