Genetic Association of Glucocorticoid Receptor Gene Polymorphisms With Binge Eating

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

91 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-01-01

Study Completion Date

2021-02-01

Brief Summary

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The aim of the present study was to specifically screen obese diabetic adolescent female individuals for BED, checking the variants of the GR gene (rs56149945; rs41423247) amongst identified individuals, and this led to assessing the impact of binge eating disorders on glycaemic control in obese diabetic adolescent females in Pakistan, South Asia.

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Detailed Description

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Challenges in eating for diabetic adolescents can be categorized as eating disorders (ED) and disordered eating symptoms (DES). Binge-eating disorder (BED) is defined as recurrent episodes of binge eating at least once a week over a three-month time period and it is accompanied by feeling the lack of control and marked distress over one's eating behaviour. The aim of the present study was to specifically screen obese diabetic adolescent female individuals for BED, checking the variants of the GR gene (rs56149945; rs41423247) amongst identified individuals, and this led to assessing the impact of binge eating disorders on glycaemic control in obese diabetic adolescent females in Pakistan, South Asia.

Conditions

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Binge-Eating Disorder Eating Disorders Obesity Diabetes Type 2 Adolescent Behavior

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SCREENING

Blinding Strategy

SINGLE

Participants

Study Groups

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Group BED

Those who are diagnosed with having Binge Eating disorder. These individuals qualified after the questionnaire was administered.

Group Type ACTIVE_COMPARATOR

BED Questionnaire

Intervention Type DIAGNOSTIC_TEST

BED Questionnaire

Group Non-BED

Those who are not diagnosed with having Binge Eating disorder

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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BED Questionnaire

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Unmarried females diagnosed with Type 2 diabetes \> 12 months
* Age 10-19 years
* Obesity class I and II (based on BMI range of 30 - 40).

Exclusion Criteria

* Presence of psychosis, major psychiatric or neurocognitive disorder
* Substance use
* Untreated attention-deficit hyperactivity disorder
* Use of psychopharmacological medications or psychotherapy
* Class III obesity

Minimum Eligible Age

10 Years

Maximum Eligible Age

19 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No