The Effects of Puberty and Weight on Sugar Metabolism in Children

NCT ID: NCT01718080

Last Updated: 2017-04-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

83 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-10-31

Study Completion Date

2015-06-30

Brief Summary

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Our goal is to investigate how hormones that control blood sugar, hunger, and stomach emptying change with puberty and being overweight. These substances change with a meal.

* For this, we need to compare lean and overweight children.
* We need to study them before and during puberty.
* All children in the study will be tested before and after a liquid meal.

Detailed Description

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Conditions

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Overweight Leanness Adolescent

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Group A

Healthy lean children before puberty

No interventions assigned to this group

Group B

Otherwise healthy overweight children before puberty

No interventions assigned to this group

Group C

Healthy lean adolescents in mid to late puberty

No interventions assigned to this group

Group D

Otherwise healthy overweight adolescents in mid to late puberty

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

All groups:

Healthy lean and otherwise healthy overweight children and adolescents between the ages of 8 and 17.

Exclusion Criteria

Same for all groups

The subjects will be excluded if they have:

* a history of chronic disease
* allergy to acetaminophen
* evidence or history of chemical abuse
* abnormal lab values
* pregnancy
Minimum Eligible Age

8 Years

Maximum Eligible Age

17 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Baylor College of Medicine

OTHER

Sponsor Role lead

Responsible Party

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Luisa M. Rodriguez

The Role of Puberty and Insulin Resistance in the Development of Hyperglucagonemia

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Luisa M. Rodriguez, MD

Role: PRINCIPAL_INVESTIGATOR

Baylor College of Medicine

Locations

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Baylor College of Medicine

Houston, Texas, United States

Site Status

Countries

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United States

Other Identifiers

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NIH 1K126K63691

Identifier Type: OTHER

Identifier Source: secondary_id

H-29652

Identifier Type: -

Identifier Source: org_study_id

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