Understanding Metabolism and Inflammation Risks for Diabetes in Adolescents
NCT ID: NCT06007404
Last Updated: 2025-05-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
175 participants
OBSERVATIONAL
2023-09-06
2027-09-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
CROSS_SECTIONAL
Study Groups
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Normal weight
BMI ≥ 5th percentile \& \< 85th percentile
No interventions assigned to this group
Obese weight
BMI ≥ 95th percentile
No interventions assigned to this group
PreDiabetes
HbA1c \> 5.7%
No interventions assigned to this group
Type 2 Diabetes
Diagnosed with Type 2 Diabetes
No interventions assigned to this group
Overweight
BMI \> 86th percentile and \<94th percentile
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* Tanner stage 4 or 5 (mature adult stage of puberty)
* Normal weight (BMI ≥ 5th percentile \& \< 85th percentile), overweight (BMI \> 86th percentile) \& \< 94th percentile), obese weight (BMI percentile ≥ 95th percentile), and/or pre-diabetes (HbA1c \> 5.7%)
* For Type 2 Diabetes cohort, diagnosis of Type 2 Diabetes
Exclusion Criteria
* Use medications known to affect glucose metabolism (immunosuppressive medications, cancer medications, or high dose steroids), unless prescribed for Type 2 Diabetes management
* Prior diagnosis of autoimmune disease, cancer, or a cognitive or perceptual disability that would inhibit following directions of study staff
* Allergies or intolerance to milk, soy, or palm oil
14 Years
18 Years
ALL
Yes
Sponsors
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National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
University of Michigan
OTHER
Responsible Party
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Kanakadurga Singer
Associate Professor
Principal Investigators
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Kanakadurga Singer, MA, MD
Role: PRINCIPAL_INVESTIGATOR
University of Michigan
Locations
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University of Michigan
Ann Arbor, Michigan, United States
Countries
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Central Contacts
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Other Identifiers
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HUM00208301
Identifier Type: -
Identifier Source: org_study_id
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