Evaluation of Blood Biomarkers as an Indicator of Delayed Neurocognitive Recovery
NCT ID: NCT04679259
Last Updated: 2026-01-20
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
82 participants
INTERVENTIONAL
2021-01-06
2025-10-29
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
DIAGNOSTIC
NONE
Study Groups
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Cardiac surgical patients
Blood sampling for assessment of the level of D-Amino Acid Oxidase, D-serine and Serine in blood
Blood sampling is done before surgery and at 1, 2, and 7 day after surgery. The level of D-Amino Acid Oxidase, D-serine and Serine in blood are assessed.
Neurocognitive test
Neurocognitive test is performed before surgery and at 7 day after surgery
Assessment of delirium
Postoperative delirium is assessed daily during 7 days after surgery.
Interventions
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Blood sampling for assessment of the level of D-Amino Acid Oxidase, D-serine and Serine in blood
Blood sampling is done before surgery and at 1, 2, and 7 day after surgery. The level of D-Amino Acid Oxidase, D-serine and Serine in blood are assessed.
Neurocognitive test
Neurocognitive test is performed before surgery and at 7 day after surgery
Assessment of delirium
Postoperative delirium is assessed daily during 7 days after surgery.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* History of psychological or neurological diseases
* Illiteracy
* Preoperative delirium
* Vision and hearing impairment
55 Years
ALL
No
Sponsors
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SMG-SNU Boramae Medical Center
OTHER
Responsible Party
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Jin-Young Hwang
Associate professor
Locations
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SMG-SNU Boramae Medical Center
Seoul, Select State/Province, South Korea
Countries
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Other Identifiers
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30-2020
Identifier Type: -
Identifier Source: org_study_id
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