Is Adipose Tissue a Reservoir for SARS-Cov2 Spread in Covid-19 Patients?

NCT ID: NCT04427878

Last Updated: 2024-06-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

5 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-08-03

Study Completion Date

2020-09-09

Brief Summary

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Resident cells of human adipose tissue express ACE2 and DPP4, receptors for SARS-Cov2. The hypothesis is that the virus may enter and spread in fat depots.

Detailed Description

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Conditions

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Covid-19 Patients

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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patients with Covid-19

Group Type EXPERIMENTAL

biopsies of subcutaneous adipose tissue

Intervention Type PROCEDURE

Two 4mm punch biopsies of subcutaneous abdominal or thight adipose tissue

Interventions

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biopsies of subcutaneous adipose tissue

Two 4mm punch biopsies of subcutaneous abdominal or thight adipose tissue

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Male or female ≥ 18 years old
* Patients testing positive for Covid19
* Patients affiliated to social security
* Signing of free and informed consent

Exclusion Criteria

* Vulnerable persons (- minors,
* adults under guardianship or curatorship,
* pregnant women,
* persons deprived of their liberty,
* persons who do not master the French language)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire de Nice

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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CHU de Nice

Nice, , France

Site Status

Countries

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France

Other Identifiers

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20-PP-15

Identifier Type: -

Identifier Source: org_study_id

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