Clinical and Molecular Aspects of Early Osteoarthritis

NCT ID: NCT04267510

Last Updated: 2020-02-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

65 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-01-01

Study Completion Date

2020-01-01

Brief Summary

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The etiology of osteoarthritis is varied, ranging from multifactorial, environmental to monogenic. In individuals in whom osteoarthritis appears earlier than in the general population, it is called early osteoarthritis. To our knowledge, there are no large-scale genetic studies on people with early osteoarthritis. The investigators therefore sought to study the causes of monogenic osteoarthritis in people suffering from early non-syndromic osteoarthritis.

Material and method From 2013 to 2019, experts in constitutional bone disease sent patients with non-syndromic early osteoarthritis for genetic analysis to our center of competence for constitutional bone diseases. The sequencing of a panel of genes was carried out by NGS.

Detailed Description

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Conditions

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Early Osteoarthritis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Eligibility Criteria

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Inclusion Criteria

\- Patients with early osteoarthritis who have undergone genetic sequencing

Exclusion Criteria

\- Patients refusing to participate in research
Minimum Eligible Age

7 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Montpellier

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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David GENEVIEVE

Role: PRINCIPAL_INVESTIGATOR

Department of Medical Genetics

Locations

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UH Montpellier

Montpellier, , France

Site Status

Countries

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France

Other Identifiers

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RECHMPL20_0085

Identifier Type: -

Identifier Source: org_study_id

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