Factors Affecting Hand Dysfunction in Patient With Rheumatoid Arthritis and Its Correlation With Quality of Life

NCT ID: NCT03274570

Last Updated: 2017-09-07

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 100 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2017-10-01
• Study Completion Date: 2019-01-31

Brief Summary

The aims of the research are:

• To predict factors affecting hand dysfunction in patient with rheumatoid arthritis
• To study the effect of hand dysfunction on quality of life in patient with rheumatoid arthritis

Detailed Description

Rheumatoid Arthritis (RA) is the most common chronic autoimmune systemic inflammatory arthritis, associated with considerable impairments of Quality of life .

Hand is the principle means by which an individual interacts with people and objects in the external environment .Many factors affect hand function in addition to arthritis ,. Many RA patients suffer from an increased loss of muscle mass with a significant impact on these patients' quality of life , and also Distal sensory, mixed sensorimotor, mononeuritis multiplex and entrapment neuropathy are the most commonly reported types of neuropathy in RA .So assessment of factors causing hand dysfunction can provide us a quick and early insight on the debilitating effects of RA on functioning and disability.Thus Early intervention can then be initiated which will help limit joint damage and thereby improve functional outcomes.

Conditions

Rheumatoid Arthritis

Study Design

• Observational Model Type: CASE_ONLY
• Study Time Perspective: CROSS_SECTIONAL

Eligibility Criteria

Inclusion Criteria

• Adult Patients who fulfilled the American College of Rheumatology (ACR) (2010) criteria for RA, attending the Rheumatology and Rehabilitation outpatient clinic and in-patient department, Faculty of Medicine, Assuit University Hospitals.

Exclusion Criteria

• Patients with other rheumatic diseases.
• Patients less than 18 years old.
• Patients with co-morbidities influencing disease activity and hand function (e.g., end- stage liver or renal disease, serious infections, or severe cardiac, respiratory, gastrointestinal disease) .
• Patient with any recent history of hand trauma, or surgery.
• Patient with neurological involvement as , peripheral neuropathy and radiculopathy

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Assiut University

OTHER

Sponsor Role: lead

Responsible Party

Essraa Mohammed

Principal Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Safaa A Mahran, professor

Role: STUDY_DIRECTOR

Assiut University

Essam Abda, professor

Role: STUDY_DIRECTOR

Assiut University

Central Contacts

Essraa abd el razek, doctor

Role: CONTACT

essraamohammed2016@yahoo.com

01009558495

Manal Hassanien, lecturer

Role: CONTACT

manal_hassanien@yahoo.com

01062679200

Other Identifiers

Hand function in RA

Identifier Type: -

Identifier Source: org_study_id