Comorbidities and Outcomes in Early Rheumatoid Arthritis

NCT ID: NCT03675516

Last Updated: 2023-07-25

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

13182 participants

Study Classification

OBSERVATIONAL

Study Start Date

2004-03-01

Study Completion Date

2017-01-01

Brief Summary

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Identify the burden of comorbidity at the time of diagnosis of rheumatoid arthritis. Identify the impact of comorbidity present at diagnosis on cardiovascular disease, death, rheumatoid arthritis disease progression and infections.

Detailed Description

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Conditions

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Rheumatoid Arthritis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Rheumatoid arthritis cases

New onset cases of rheumatoid arthritis

No specific intervention

Intervention Type OTHER

Usual care

Controls

Age, gender and primary care practice-matched controls

No specific intervention

Intervention Type OTHER

Usual care

Interventions

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No specific intervention

Usual care

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Diagnosis of rheumatoid arthritis prior to 1st January 2017
* Aged ≥18 years old

Exclusion Criteria

* Patients with another other rheumatic disease
Minimum Eligible Age

10 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Momentum Data

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Andy McGovern, BSc

Role: STUDY_DIRECTOR

Momentum Data

Locations

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Momentum Data Ltd

London, , United Kingdom

Site Status

Countries

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United Kingdom

References

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Nikiphorou E, de Lusignan S, Mallen CD, Khavandi K, Bedarida G, Buckley CD, Galloway J, Raza K. Cardiovascular risk factors and outcomes in early rheumatoid arthritis: a population-based study. Heart. 2020 Oct;106(20):1566-1572. doi: 10.1136/heartjnl-2019-316193. Epub 2020 Mar 24.

Reference Type RESULT
PMID: 32209618 (View on PubMed)

Nikiphorou E, de Lusignan S, Mallen C, Roberts J, Khavandi K, Bedarida G, Buckley CD, Galloway J, Raza K. Prognostic value of comorbidity indices and lung diseases in early rheumatoid arthritis: a UK population-based study. Rheumatology (Oxford). 2020 Jun 1;59(6):1296-1305. doi: 10.1093/rheumatology/kez409.

Reference Type RESULT
PMID: 31580449 (View on PubMed)

Nikiphorou E, de Lusignan S, Mallen C, Khavandi K, Roberts J, Buckley CD, Galloway J, Raza K. Haematological abnormalities in new-onset rheumatoid arthritis and risk of common infections: a population-based study. Rheumatology (Oxford). 2020 May 1;59(5):997-1005. doi: 10.1093/rheumatology/kez344.

Reference Type RESULT
PMID: 31501866 (View on PubMed)

Other Identifiers

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P001

Identifier Type: -

Identifier Source: org_study_id

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