Hemodynamic Effects of Negative Pressure Ventilation in Chronic Obstructive Pulmonary Disease

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-01-01

Study Completion Date

2019-12-31

Brief Summary

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Negative pressure ventilation (NPV) is a non-invasive ventilation mode which provide better lung expansion. The major complication of NPV is decrease blood pressure and affects the hemodynamics. The effects of NPV on chronic obstructive pulmonary disease (COPD) patients with pulmonary rehabilitation program remains unknown.

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Detailed Description

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Both of NPV or positive pressure ventilation (PPV) has impact of hemodynamics. NPV with cuirass ventilator increases venous return and leads to ventricular filling and increases cardiac output (CO); In contrast to NPV, the effect of PPV in most situations is a decreased venous return and leads to decreased CO. NPV improving ventilation and work of breathing in patients with chronic obstructive pulmonary disease (COPD).

Conditions

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COPD

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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NPV group

Patients who had treated in pulmonary rehabilitation unit with NPV

Received negative pressure ventilation

Intervention Type OTHER

Patients who received a negative pressure during inspiratory phase.

Interventions

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Received negative pressure ventilation

Patients who received a negative pressure during inspiratory phase.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients with COPD who received pulmonary rehabilitation program with NPV treatment

Exclusion Criteria

* Recent exacerbation within 3-months
* Existing of tracheostomy
* Absence of NPV used
* Required of oxygen supplement during NPV
* Diagnosed of neuromuscular disease

Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No