Effect of Pressure Support Ventilation and Neurally Adjusted Ventilatory Assist (NAVA) in Chronic Obstructive Pulmonary Disease (COPD) Patients

NCT ID: NCT00568100

Last Updated: 2015-04-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

15 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-04-30

Study Completion Date

2014-11-30

Brief Summary

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The investigators' aim is to study the effect of pressure support ventilation at two levels of PEEP and Pressure Support versus neurally adjusted ventilatory assist (NAVA) in COPD patients.

Detailed Description

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In this study, two levels of pressure support and PEEP during pressure support ventilation are compared with neurally adjusted ventilatory assist (NAVA) in COPD patients by measuring respiratory mechanics, intrinsic PEEP, work of breathing and patient's level of comfort.

Conditions

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Chronic Obstructive Pulmonary Disease

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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1

COPD patients

Group Type EXPERIMENTAL

PSV and NAVA

Intervention Type PROCEDURE

evaluated the effect of PSV and NAVA on breathing pattern, respiratory effort, gas exchange and level of breathing comfort in COPD patients

Interventions

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PSV and NAVA

evaluated the effect of PSV and NAVA on breathing pattern, respiratory effort, gas exchange and level of breathing comfort in COPD patients

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Stable COPD patients during non invasive mechanical ventilation

Exclusion Criteria

* Haemodynamic instability
* Coma
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Policlinico Hospital

OTHER

Sponsor Role lead

Responsible Party

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Davide Chiumello

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Davide Chiumello, MD

Role: PRINCIPAL_INVESTIGATOR

Policlinico Hospital

Locations

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Policlinico Hospital

Milan, , Italy

Site Status

Countries

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Italy

Other Identifiers

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2222

Identifier Type: -

Identifier Source: org_study_id

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