Neurally Adjusted Ventilatory Assist and Synchrony in Patients With Chronic Obstructive Pulmonary Disease (COPD)
NCT ID: NCT01042080
Last Updated: 2019-09-06
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
16 participants
INTERVENTIONAL
2009-12-31
2019-09-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
SUPPORTIVE_CARE
NONE
Study Groups
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PSV-ET 25
Pressure support ventilation with expiratory trigger set at 25 %.
Expiratory trigger (ET)
Varying the cycling criterion according to the percentage of peak inspiratory flow
PSV-ET 50
Pressure support ventilation with expiratory cycling set at 50 %.
Expiratory trigger (ET)
Varying the cycling criterion according to the percentage of peak inspiratory flow
NAVA
NAVA level is adjusted to achieve similar peak inspiratory pressure levels than during PSV.
NAVA
Assisted mechanical ventilation according to the electrical activity of the diaphragm recorded with a 16-FR naso-gastric tube mounted with EMG electrodes
Interventions
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NAVA
Assisted mechanical ventilation according to the electrical activity of the diaphragm recorded with a 16-FR naso-gastric tube mounted with EMG electrodes
Expiratory trigger (ET)
Varying the cycling criterion according to the percentage of peak inspiratory flow
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Admitted for acute respiratory failure requiring invasive mechanical ventilation
* Currently receiving pressure support ventilation
Exclusion Criteria
* Respiratory rate \> 35 bpm
* Severe hypoxemia with SpO2 \< 88 % and FIO2 \> 50 %
* Heart rate \> 120 bpm
* Systolic arterial pressure \< 90 mmHg
* Contraindication to naso-gastric tube's insertion
18 Years
ALL
No
Sponsors
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Hôpital Européen Marseille
OTHER
Responsible Party
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Jerome Allardet-Servent, MD
MD, MSc
Principal Investigators
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Jérôme ALLARDET-SERVENT, MD, MSc
Role: PRINCIPAL_INVESTIGATOR
Fondation Hôpital Ambroise Paré
Locations
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Hopital Paul Desbief
Marseille, , France
Fondation Hôpital Ambroise Paré
Marseille, , France
Countries
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Other Identifiers
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2009-A01099-48
Identifier Type: -
Identifier Source: org_study_id
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