Negative Pressure Ventilation Imapcts Weaning Ventilator In Medical Intensive Care Units (ICUs)

NCT ID: NCT01155596

Last Updated: 2010-07-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE2

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-03-31

Study Completion Date

2011-03-31

Brief Summary

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This is a Quasi-experimental research design. The subjects are limited in intensive care unit within north medical center hospital. All subjects depend on ventilator and receive weaning plans. Experimental group is weaning with the support of negative pressure ventilator .The investigators collect basic personal variables in the questionnaire, APACHE Ⅱ scale, Dyspnea scale and arterial blood gas analysis and ventilator weaning index. Compare experimental group and control group data. Data will be Statistical analyzed by: descriptive statistics (such as: mean, standard deviation, median, frequency, percentage) and inferential statistics (such as: Independent T-test, Pair T-test, Mann-Whitney U test), P-value \<0.05 will consider to be statistically significant.

Detailed Description

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Conditions

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Respiratory Failure

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SCREENING

Blinding Strategy

NONE

Study Groups

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Control group

Base on positive pressure ventilation with intubation and mechanical ventilator, weaning processes will undergo by Pulmonologists.

Group Type NO_INTERVENTION

No interventions assigned to this group

Experimental group

Experimental group is weaning with the support of negative pressure ventilator.

Group Type EXPERIMENTAL

negative pressure ventilator use

Intervention Type BEHAVIORAL

Body ventilators that assist ventilation by applying intermittent subatmospheric pressure around the thorax, abdomen, or airway and periodically expand the chest wall and inflate the lungs. They are relatively simple to operate and do not require tracheostomy. Chest cuirass is used in this study.

Interventions

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negative pressure ventilator use

Body ventilators that assist ventilation by applying intermittent subatmospheric pressure around the thorax, abdomen, or airway and periodically expand the chest wall and inflate the lungs. They are relatively simple to operate and do not require tracheostomy. Chest cuirass is used in this study.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Acute respiratory failure patients in medical ICUs

Exclusion Criteria

* Age\<20 years old
* Malignancy
* Pregnancy
Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Chang Gung Memorial Hospital

OTHER

Sponsor Role lead

Responsible Party

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Chang Gung Memorial Hospital

Locations

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Gung Memorial Hospital, Chang Gung University, College of Medicine.

Taipei, , Taiwan

Site Status RECRUITING

Countries

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Taiwan

Central Contacts

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Horng-Chyuan Lin

Role: CONTACT

Facility Contacts

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Horng-Chyuan Lin

Role: primary

Other Identifiers

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98-3276B

Identifier Type: -

Identifier Source: org_study_id

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