Weaning Outcome From Invasive Mechanical Ventilation

NCT ID: NCT02981589

Last Updated: 2021-07-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-07-31

Study Completion Date

2024-03-31

Brief Summary

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The main purpose of the present study was to explore the weaning failure rate from invasive mechanical ventilation and to identify risk factors of weaning failure.

Detailed Description

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Conditions

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Patients Requiring Endotracheal Intubation and Invasive Mechanical Ventilation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Invasive mechanical ventilation

Invasive ventilation was performed to all eligible patients. When patients met predefined criteria, spontaneous breathing trial was performed. Given spontaneous breathing trial passed, patients were extubated; on the contrary, patients would continue to receive invasive ventilation. If patients had respiratory failure after extubation, reintubation and invasive ventilation were necessary.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Requiring endotracheal intubation and invasive mechanical ventilation

Exclusion Criteria

* Duration of invasive mechanical ventilation \< 48 hours;
* Presence of tracheostomy;
* Presence of upper airway obstruction.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Beijing Chao Yang Hospital

OTHER

Sponsor Role lead

Responsible Party

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Zujin Luo

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Zujin Luo, MD

Role: PRINCIPAL_INVESTIGATOR

Beijing Chao Yang Hospital

Locations

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Respiratory intensive care unit, Beijing Chao Yang Hospital Jingxi Campus

Beiling, , China

Site Status RECRUITING

Countries

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China

Central Contacts

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Zujin Luo, MD

Role: CONTACT

Facility Contacts

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Zujin Luo, MD

Role: primary

References

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Luo Z, Zheng Y, Yang L, Liu S, Zhu J, Zhao N, Pang B, Cao Z, Ma Y. Neutrophil/lymphocyte ratio is helpful for predicting weaning failure: a prospective, observational cohort study. J Thorac Dis. 2018 Sep;10(9):5232-5245. doi: 10.21037/jtd.2018.08.68.

Reference Type DERIVED
PMID: 30416770 (View on PubMed)

Other Identifiers

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BeijingCYH-ICU-003

Identifier Type: -

Identifier Source: org_study_id

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