Volume Responsiveness Before SBT Predicts the Outcome of Mechanical Ventilation Weaning in Critically Ill Patients
NCT ID: NCT01867853
Last Updated: 2013-06-05
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
82 participants
OBSERVATIONAL
2012-10-31
2013-03-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_ONLY
PROSPECTIVE
Study Groups
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successful weaning
the SUCCESS of SBT or not need for reintubation or noninvasive ventilation within 48 h following extubation
PLR
passive leg raising test was done before and at the end of SBT
failed weaning
the failure of SBT or the need for reintubation or noninvasive ventilation within 48 h following extubation
PLR
passive leg raising test was done before and at the end of SBT
Interventions
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PLR
passive leg raising test was done before and at the end of SBT
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* tracheostomy at baseline
* myasthenia gravis or acute polyradiculoneuropathy
* end-stage chronic illness
18 Years
ALL
Yes
Sponsors
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Zhongda Hospital
OTHER
Southeast University, China
OTHER
Responsible Party
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Jianfeng Xie
Director
Principal Investigators
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Zhimin DOU
Role: PRINCIPAL_INVESTIGATOR
Southeast University
Locations
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Zhongda hospital
Nanjing, Jiangsu, China
Countries
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References
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MacIntyre N. Discontinuing mechanical ventilatory support. Chest. 2007 Sep;132(3):1049-56. doi: 10.1378/chest.06-2862.
Eskandar N, Apostolakos MJ. Weaning from mechanical ventilation. Crit Care Clin. 2007 Apr;23(2):263-74, x. doi: 10.1016/j.ccc.2006.12.002.
MacIntyre NR, Cook DJ, Ely EW Jr, Epstein SK, Fink JB, Heffner JE, Hess D, Hubmayer RD, Scheinhorn DJ; American College of Chest Physicians; American Association for Respiratory Care; American College of Critical Care Medicine. Evidence-based guidelines for weaning and discontinuing ventilatory support: a collective task force facilitated by the American College of Chest Physicians; the American Association for Respiratory Care; and the American College of Critical Care Medicine. Chest. 2001 Dec;120(6 Suppl):375S-95S. doi: 10.1378/chest.120.6_suppl.375s. No abstract available.
Monnet X, Teboul JL, Richard C. Cardiopulmonary interactions in patients with heart failure. Curr Opin Crit Care. 2007 Feb;13(1):6-11. doi: 10.1097/MCC.0b013e328013c865.
Teboul JL, Monnet X. Detecting volume responsiveness and unresponsiveness in intensive care unit patients: two different problems, only one solution. Crit Care. 2009;13(4):175. doi: 10.1186/cc7979. Epub 2009 Aug 10.
Monnet X, Teboul JL. Passive leg raising. Intensive Care Med. 2008 Apr;34(4):659-63. doi: 10.1007/s00134-008-0994-y. Epub 2008 Jan 23.
Other Identifiers
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10286
Identifier Type: -
Identifier Source: org_study_id
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