Maximal Inspiratory Pressure at Extubation: Relationship With Mortality

NCT ID: NCT02363231

Last Updated: 2016-01-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

124 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-01-31

Study Completion Date

2016-01-31

Brief Summary

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The process of weaning from mechanical ventilation was decided after clinical judgment and weaning predictive index. Nevertheless, indexes predicting weaning outcome like Maximal Inspiratory Pressure (MIP) are frequently inaccurate. However the long-term involvement of respiratory muscles in critically ill patients has not been established. The objective of this study was to assess the relationship on MIP at extubation on one-year mortality in critically ill patients.

Detailed Description

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Conditions

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Mechanical Ventilation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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patients under mechanical ventilation

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Mechanical ventilation at least at 24 hours

Exclusion Criteria

* Delirium
* Cognitive dysfunction
* refusal to participate
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Rouen

OTHER

Sponsor Role lead

Responsible Party

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BOUCHRA LAMIA

MD, PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Clement Medrinal

Role: PRINCIPAL_INVESTIGATOR

Groupe Hospitalier du Havre

Locations

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Le Havre, Jacques Monod Hospital

Montivilliers, , France

Site Status

Countries

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France

References

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Combret Y, Prieur G, Hilfiker R, Gravier FE, Smondack P, Contal O, Lamia B, Bonnevie T, Medrinal C. The relationship between maximal expiratory pressure values and critical outcomes in mechanically ventilated patients: a post hoc analysis of an observational study. Ann Intensive Care. 2021 Jan 13;11(1):8. doi: 10.1186/s13613-020-00791-4.

Reference Type DERIVED
PMID: 33438092 (View on PubMed)

Medrinal C, Prieur G, Combret Y, Quesada AR, Bonnevie T, Gravier FE, Frenoy E, Contal O, Lamia B. Reliability of respiratory pressure measurements in ventilated and non-ventilated patients in ICU: an observational study. Ann Intensive Care. 2018 Jan 30;8(1):14. doi: 10.1186/s13613-018-0362-1.

Reference Type DERIVED
PMID: 29380080 (View on PubMed)

Medrinal C, Prieur G, Frenoy E, Robledo Quesada A, Poncet A, Bonnevie T, Gravier FE, Lamia B, Contal O. Respiratory weakness after mechanical ventilation is associated with one-year mortality - a prospective study. Crit Care. 2016 Jul 31;20(1):231. doi: 10.1186/s13054-016-1418-y.

Reference Type DERIVED
PMID: 27475524 (View on PubMed)

Other Identifiers

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2013-A01157-38

Identifier Type: -

Identifier Source: org_study_id

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