Evaluation of a Combined Model in Predicting Weaning Outcome in Critically Ill Patients.

NCT ID: NCT05431036

Last Updated: 2022-10-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-11-01

Study Completion Date

2024-09-01

Brief Summary

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The purpose of our study is to assess lung aeration and diaphragmatic indices by transthoracic ultrasonography in patients ready to be weaned from mechanical ventilation as predictors of weaning success

Detailed Description

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Assessment of lung aeration and diaphragmatic indices by transthoracic ultrasonography in patients ready to be weaned from mechanical ventilation as predictors of weaning success in critically ill patients .

Conditions

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Weaning Failure

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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transthoracic ultrasonography

1. The lung ultrasound score (LUS) will be calculated according to the observed worst ultrasound pattern and Finally, the LUSs of all the parts will added to obtain the total LUS for each patient (maximum36 points)
2. The diaphragmatic ultrasound will performed for assessment of diaphragmatic thickness and motion.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patients more than18 years old.
* All patients intubated and requiring mechanical ventilation for 48 hours or more at respiratory intensive care unit (RICU)
* Patients fullfiled the criteria of readiness to wean according to European Respiratory Society guidelines (ERS)

Exclusion Criteria

* Patients with neuromuscular disease or diaphragmatic paralysis.
* Patients with tracheostomy.
* Patients who undergone surgical operations especially abdominal and thoracic operation.
* Patients with diseases that may affect the diaphragm (including pneumothorax, pneumomediastinum, patients with inserted intercostal tube (ICT), third trimester of pregnancy).
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Alaa Mohammed Taghyan

Assistant lecturer, chest department,Principal Investigator,Clinical Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Alaa M Taghyan, Ass.Lecturer

Role: PRINCIPAL_INVESTIGATOR

Chest department at Assuit university hospital

Central Contacts

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Alaa M Taghyan, master

Role: CONTACT

01093093050

Gamal M Rabee Agamy, Professor

Role: CONTACT

01155213224

References

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Matamis D, Soilemezi E, Tsagourias M, Akoumianaki E, Dimassi S, Boroli F, Richard JC, Brochard L. Sonographic evaluation of the diaphragm in critically ill patients. Technique and clinical applications. Intensive Care Med. 2013 May;39(5):801-10. doi: 10.1007/s00134-013-2823-1. Epub 2013 Jan 24.

Reference Type BACKGROUND
PMID: 23344830 (View on PubMed)

Soummer A, Perbet S, Brisson H, Arbelot C, Constantin JM, Lu Q, Rouby JJ; Lung Ultrasound Study Group. Ultrasound assessment of lung aeration loss during a successful weaning trial predicts postextubation distress*. Crit Care Med. 2012 Jul;40(7):2064-72. doi: 10.1097/CCM.0b013e31824e68ae.

Reference Type BACKGROUND
PMID: 22584759 (View on PubMed)

Li S, Chen Z, Yan W. Application of bedside ultrasound in predicting the outcome of weaning from mechanical ventilation in elderly patients. BMC Pulm Med. 2021 Jul 9;21(1):217. doi: 10.1186/s12890-021-01605-4.

Reference Type BACKGROUND
PMID: 34243739 (View on PubMed)

Other Identifiers

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lung US in ICU patient

Identifier Type: -

Identifier Source: org_study_id

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