Weaning From Mechanical Ventilation in Patients With Acute Brain Injury
NCT ID: NCT06542107
Last Updated: 2025-11-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
406 participants
OBSERVATIONAL
2024-08-06
2025-12-31
Brief Summary
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Numerous studies have explored the causes of weaning failure and provide various predictive models in guiding extubation and tracheostomy. Yet, due to limitations of such as small sample size or a lack of external validation, there is paucity of practical weaning algorithm tailored for ABI patients. The liberation from IMV in ABI patients still remains challenging with poor level of evidence in current guidelines or expert consensus.
We aim to describe the weaning outcomes in ABI patients, and further investigate the potential predictors of weaning success in ABI patients.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
* age \>=18 years
* invasive mechanical ventilation for at least 24 hours
Exclusion Criteria
* pregnant or lactation
* with cervical spinal cord injury
* decision to receive palliative care within 24 hours of ICU admission
18 Years
ALL
No
Sponsors
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Southeast University, China
OTHER
Responsible Party
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Ling Liu
Director of Intensive Care Unit, Principal Investigator, Clinical Professor
Locations
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Ling Liu
Nanjing, Jiangsu, China
Department of Critical Care Medicine, Zhongda Hospital
Nanjing, , China
Countries
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Central Contacts
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Facility Contacts
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Ling Liu
Role: primary
Other Identifiers
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WEAN ABI
Identifier Type: -
Identifier Source: org_study_id
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