Criteria of Extubation Failure of Brain Injured Patients. Elaboration of a Prognostic Score.
NCT ID: NCT02235376
Last Updated: 2015-10-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
140 participants
OBSERVATIONAL
2013-06-30
2015-09-30
Brief Summary
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Detailed Description
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Identification of clinical and biological criteria associated with failure of extubation.
Elaboration of a prognostic score of extubation failure of brain injured patients, based on criteria previously identified with multivariate analysis.
Failure of extubation is defined by the need of re-intubation or the need for non-invasive ventilation within 48 hours or more after extubation.
Conditions
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Study Design
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PROSPECTIVE
Study Groups
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critical care
weaning trial of mechanical ventilation
Interventions
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weaning trial of mechanical ventilation
Eligibility Criteria
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Inclusion Criteria
* Stable respiratory and hemodynamic conditions
* Ventilated patients for more than 48 hours
* Adequate gaseous exchange (SpO2 ≥ 92% and respiratory rate ≤ 35/min, FiO2 ≤ 40%, positive end-expiratory pressure ≤ 5 cmH2O, pressure support ≤ 8 cmH2O, tidal volume ≥ 7mL/kg
* Therapeutic extubation
Exclusion Criteria
* Cerebrospinal infection
* Patients under 15 years old
* Mechanical ventilation of \< 48 h
* Spinal cord injury
* Withdrawal of life support
15 Years
ALL
No
Sponsors
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University Hospital, Clermont-Ferrand
OTHER
Responsible Party
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Principal Investigators
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Russell CHABANNE
Role: PRINCIPAL_INVESTIGATOR
University Hospital, Clermont-Ferrand
Locations
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CHU de Clermont-Ferrand
Clermont-Ferrand, , France
Countries
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Other Identifiers
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CHU-0201
Identifier Type: -
Identifier Source: org_study_id
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