A Protocol to Wean From Noninvasive Mechanical Ventilation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-07-31

Study Completion Date

2011-05-31

Brief Summary

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The investigators use a protocol to wean from noninvasive mechanical ventilation.

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Detailed Description

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Design: Prospective, randomized, controlled trial, with 2 groups: study (protocol weaning group) and control (clinicians' order weaning group). Setting: Respiratory Intensive Care Unit (RICU). Subjects: Patients \>18 yr, noninvasive mechanical ventilation \>24 hours. Interventions and measurements: Study group (weaning as the protocol) and control group (weaning as the clinicians' order); recording of clinical variables at admission and during RICU stay, and end-point variables (noninvasive mechanical ventilation day, RICU and hospital stay, RICU mortality. Expected results: the protocol group's noninvasive mechanical ventilation days is less than clinicians' order group.

Conditions

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Ventilator Weaning

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SCREENING

Blinding Strategy

NONE

Study Groups

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protocol group

This group patients are weaned as the protocol which the investigators described.

Group Type ACTIVE_COMPARATOR

protocol

Intervention Type DEVICE

In this group, the patients were weaned as the protocol.

clinicians' order group

This group patients are weaned as the clinicians' order.

Group Type OTHER

physician's orders

Intervention Type OTHER

In this group, the patients were weaned as the clinicians' order.

Interventions

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protocol

In this group, the patients were weaned as the protocol.

Intervention Type DEVICE

physician's orders

In this group, the patients were weaned as the clinicians' order.

Intervention Type OTHER

Other Intervention Names

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In this group, the patients were weaned as the protocol. In this group, the patients were weaned as the clinicians' order.

Eligibility Criteria

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Inclusion Criteria

1. noninvasive mechanical ventilation \> 24 hours.
2. age \>18 years

Exclusion Criteria

1. severe cerebraI，heart，hepatic and renal faiIure.
2. facial or cranial trauma or surgery.
3. facial abnormalities.
4. recent gastric or esophageal surgery.
5. active upper gastrointestinal bleeding.
6. large amount of sputum with weak cough ability
7. lack of co-operation.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No