A Cluster Randomized Trial to Improve Weaning and Extubation From Mechanical Ventilation in Community Hospitals

NCT ID: NCT00157287

Last Updated: 2017-08-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Study Classification

INTERVENTIONAL

Study Start Date

2003-06-30

Study Completion Date

2006-04-30

Brief Summary

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Protocol directed weaning has been shown to reduce the duration of mechanical ventilation for patients admitted to the intensive care unit (ICU) of tertiary centres. However, this benefit has not previously been studied in a community hospital setting. We therefore sought to evaluate the impact of an evidence-based weaning guideline on the outcomes for patients receiving mechanical ventilation in the ICUs of community hospitals in a cluster randomized controlled trial involving 11 community hospitals.

Detailed Description

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Conditions

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Respiration, Artificial

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Interventions

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Evidence based weaning protocol

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* patients ventilated for more than 24 hours

Exclusion Criteria

* patients less than 16 years of age patients who receive only non-invasive ventilation patients chronically ventilated at time of ICU admission patients who will not be candidates for weaning from ventilation at time of admission If withdrawl of life support is imminent at the point the patient has been ventilated for 24 hours
Minimum Eligible Age

16 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Ronald J Butler, MD

Role: PRINCIPAL_INVESTIGATOR

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Claudio Martin, MD

Role: PRINCIPAL_INVESTIGATOR

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Femida Gwadry-Sridhar, MSc

Role: PRINCIPAL_INVESTIGATOR

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Locations

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William Osler Health Centre (Brampton)

Brampton, Ontario, Canada

Site Status

Brant Community Health Systems

Brantford, Ontario, Canada

Site Status

Joseph Brant Memorial Hospital

Burlington, Ontario, Canada

Site Status

Guelph General Hospital

Guelph, Ontario, Canada

Site Status

St. Joseph's Health Care

London, Ontario, Canada

Site Status

Trillium Health Centre

Mississauga, Ontario, Canada

Site Status

North Bay General Hospital

North Bay, Ontario, Canada

Site Status

Lakeridge Health Corporation (Oshawa)

Oshawa, Ontario, Canada

Site Status

Stratford General Hospital

Stratford, Ontario, Canada

Site Status

St. Joseph's Health Centre

Toronto, Ontario, Canada

Site Status

Hotel Dieu of St. Joseph

Windsor, Ontario, Canada

Site Status

Countries

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Canada

Other Identifiers

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R-01-076

Identifier Type: -

Identifier Source: org_study_id

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