Evaluation of a Systematic Approach to Weaning From Mechanical Ventilation

NCT ID: NCT01482429

Last Updated: 2013-03-04

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

235 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-01-31

Study Completion Date

2012-01-31

Brief Summary

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Prolongation of mechanical ventilation poses serious personal and financial threats to healthcare consumers.

The investigators objectives are create and implement an multidisciplinary evidenced-based ventilator-weaning protocol to assess whether a systematic approach compared with the physician's judgment only decreases time spent on the ventilator, complications of mechanical ventilation and length of stay in critical care unit.

Detailed Description

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Conditions

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Weaning Failure Complication of Respirator [Ventilator]

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Blinding Strategy

NONE

Study Groups

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Protocol-directed

Discontinuation of ventilation was based in multidisciplinary protocol.

Group Type EXPERIMENTAL

Multidisciplinary weaning-ventilator protocol

Intervention Type OTHER

We implemented a multidisciplinary protocol for weaning from mechanical ventilation.This consist of a daily screening for readiness, performing a spontaneous breathing test, evaluation of signs of intolerance and decision on extubation.

Usual care

Discontinuation of ventilation was left entirely to the discretion of the physicians.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Multidisciplinary weaning-ventilator protocol

We implemented a multidisciplinary protocol for weaning from mechanical ventilation.This consist of a daily screening for readiness, performing a spontaneous breathing test, evaluation of signs of intolerance and decision on extubation.

Intervention Type OTHER

Other Intervention Names

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Weaning-ventilator protocol

Eligibility Criteria

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Inclusion Criteria

* remain in mechanical ventilation for more than 24 hours
* begin weaning from mechanical ventilation

Exclusion Criteria

* admitted in the unit already in weaning from mechanical ventilation
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Federal University of Uberlandia

OTHER

Sponsor Role lead

Responsible Party

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Liliane Barbosa da Silva Passos

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Liliane Barbosa da Silva Passos

Role: PRINCIPAL_INVESTIGATOR

Federal University of Uberlandia

Thulio Marquez Cunha

Role: STUDY_CHAIR

Federal University of Uberlandia

Carlos Henrique Alves de Rezende, MD

Role: STUDY_CHAIR

Federal University of Uberlandia

Locations

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Federal University of Uberlandia

Uberlândia, Minas Gerais, Brazil

Site Status

Countries

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Brazil

Other Identifiers

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Desmame

Identifier Type: -

Identifier Source: org_study_id

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