Comparison of Volume Assist Control, Dual Mode and Airway Pressure Release Ventilation.
NCT ID: NCT04196738
Last Updated: 2024-01-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
20 participants
INTERVENTIONAL
2020-06-30
2022-10-26
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
OTHER
NONE
Study Groups
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Dual Mode first
Four consecutive steps (45 min per step) in the following order: APRV (A), Dual Mode (B) , APRV (A) and VAC (C). (ABAC)
ventilation strategy
Patients are ventilated in randomised order with three different ventilation strategies: volume assist control (constant flow), Dual Mode or Airway Pressure Released Ventilation
VAC fist
Four consecutive steps (45 min per step) in the following order: APRV (A), VAC (C) , APRV (A) and Dual Mode (B). (ACAB)
ventilation strategy
Patients are ventilated in randomised order with three different ventilation strategies: volume assist control (constant flow), Dual Mode or Airway Pressure Released Ventilation
Interventions
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ventilation strategy
Patients are ventilated in randomised order with three different ventilation strategies: volume assist control (constant flow), Dual Mode or Airway Pressure Released Ventilation
Eligibility Criteria
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Inclusion Criteria
* Invasive mechanical ventilation on tracheal probe
* Acute respiratory distress syndrome, as defined by Berlin conference consensus, during hospitalization in intensive care,
* Recovery phase of acute respiratory distress syndrome: spontaneous ventilation representing from 20 to 30% of ventilation in APRV mode.
* No severe acidosis (pH\> 7.30)
* Patient affiliated to or beneficiary of a health care plan
* Express consent of the patient or his/her SDM
Exclusion Criteria
* Contraindication to the insertion of a nasogastric tube with an esophageal balloon
* Contraindication to the use of Electrical impedance tomography (pacemaker)
* Pregnancy, lactating or parturient woman
18 Years
ALL
No
Sponsors
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University Hospital, Angers
OTHER_GOV
Responsible Party
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Principal Investigators
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Francois BELONCLE, CCU-AH
Role: PRINCIPAL_INVESTIGATOR
Angers teatching hospital
Locations
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University hospital
Angers, , France
Countries
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Other Identifiers
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49RC19_0195
Identifier Type: -
Identifier Source: org_study_id
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