Feasabilty and Physiological Effects of a Ventilation Strategy Combining PEEP and Tidal Volume Titration According to Inspiratory and Expiratory Transpulmonary Pressures in ARDS Patients.
NCT ID: NCT05337059
Last Updated: 2022-04-20
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
25 participants
INTERVENTIONAL
2022-03-30
2024-04-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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Transpulmonary based ventilation strategy
PEEP and tidal volume will be set to target expiratory and inspiratory transpulmonary pressures of 0 and 20 cmH2O, respectively.
PEEP and Tidal Volume Titration
PEEP and Tidal Volume Titration According to Inspiratory and Expiratory Transpulmonary Pressures
Interventions
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PEEP and Tidal Volume Titration
PEEP and Tidal Volume Titration According to Inspiratory and Expiratory Transpulmonary Pressures
Eligibility Criteria
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Inclusion Criteria
* Moderate to severe ARDS
* Written informed consent obtained from patient' surrogates
Exclusion Criteria
* Known pregnancy
* Contraindication to electrical impedance tomography or esophageal pressure measurements
18 Years
ALL
No
Sponsors
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University Hospital, Angers
OTHER_GOV
Responsible Party
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Locations
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Chu Angers
Angers, , France
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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2019-A03242-55
Identifier Type: -
Identifier Source: org_study_id
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