Prognostic Value of Respiratory System Compliance Under VV-ECMO on 180-day Mortality in COVID-19 ARDS.

NCT ID: NCT05341687

Last Updated: 2024-07-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

122 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-01-03

Study Completion Date

2023-05-01

Brief Summary

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Mortality of patients with COVID-19 associated acute respiratory distress syndrome (CARDS) treated with veno-venous extra-corporal membrane oxygenation (vv-ECMO) is increasing over time since the beginning of the COVID-19 pandemic. The objectives were to retrospectively describe over the first ten days after vv-ECMO implantation, the ventilatory management of CARDS and to assess the impact of static respiratory system compliance (CRS) on the first day of vv-ECMO on 180-day mortality.

Detailed Description

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Conditions

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Ards Mechanical Ventilation Pressure High Extracorporeal Membrane Oxygenation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

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No applicable

No applicable

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients with ARDS secondary to COVID-19 pneumonia requiring ECMO-VV support, hospitalized in the intensive care units of the CHRU of Nancy, Marseille or Bordeaux between 01/03/2020 and 31/12/2021.
* Age \> 18 years old

Exclusion Criteria

* Respiratory parameters not available on ten first day of VV ECMO implantation.
* Patient refusal to participate in the study
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Central Hospital, Nancy, France

OTHER

Sponsor Role lead

Responsible Party

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Matthieu KOSZUTSKI

Principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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CHU Nancy

Nancy, , France

Site Status

Countries

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France

Other Identifiers

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2022PI050

Identifier Type: -

Identifier Source: org_study_id

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