Effects of Eccentric Training Intervention in Older Adults
NCT ID: NCT04099316
Last Updated: 2019-09-23
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
27 participants
INTERVENTIONAL
2017-07-20
2019-10-31
Brief Summary
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Detailed Description
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1. Examine the effects of eccentric training on physical function (gait speed, stair climb, chair stand) in older adults.
2. Examine the effects of eccentric training on muscle strength (Isometric strength, Isokinetic strength, power) in older adults.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
SUPPORTIVE_CARE
TRIPLE
Study Groups
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Older adults
Older adults (Over the 60 years), Subjects did not suffer from musculoskeletal or metabolic diseases.
Eccentric exercise
Eccentric exercise with Eccentron electronic device. Exercise intervention: The exercise intervention is performed to twice a week (Total 8 weeks). Exercise intensity is gradually increased to the number of times by divided into two stages (1-4 weeks; 1st stage),(5-8 weeks; 2nd stage).
Older adults-Control
Older adults (Over the 60 years), Subjects did not suffer from musculoskeletal or metabolic diseases.
Conventional resistance exercise
Leg press exercise with leg press machine. Exercise intervention: The exercise intervention is performed to twice a week (total 8 weeks). Exercise intensity is gradually increased to the number of times by divided into two stages (1-4 weeks; 1st stage), (5-8 weeks; 2nd stage).
No intervention
Metabolic diseases, Hypertension (150/90mmHg), Myocardial infarction within 6 months. Fractures within 6 months.
No interventions assigned to this group
Interventions
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Eccentric exercise
Eccentric exercise with Eccentron electronic device. Exercise intervention: The exercise intervention is performed to twice a week (Total 8 weeks). Exercise intensity is gradually increased to the number of times by divided into two stages (1-4 weeks; 1st stage),(5-8 weeks; 2nd stage).
Conventional resistance exercise
Leg press exercise with leg press machine. Exercise intervention: The exercise intervention is performed to twice a week (total 8 weeks). Exercise intensity is gradually increased to the number of times by divided into two stages (1-4 weeks; 1st stage), (5-8 weeks; 2nd stage).
Eligibility Criteria
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Inclusion Criteria
* Older men/women: Age (60 - 80 yrs)
Exclusion Criteria
* Acute coronary syndrome
* Subjects who took drugs which can affects neuromuscular system
* Subjects who cannot agree voluntarily
60 Years
80 Years
ALL
Yes
Sponsors
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National Research Foundation of Korea
OTHER
Seoul National University Bundang Hospital
OTHER
Responsible Party
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Jae-Young Lim
Professor, Department of Rehabilitation Medicine
Locations
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Seoul National University Bundang Hospital
Seongnam, Geyonggi, South Korea
Countries
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Central Contacts
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Facility Contacts
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References
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Roig M, Macintyre DL, Eng JJ, Narici MV, Maganaris CN, Reid WD. Preservation of eccentric strength in older adults: Evidence, mechanisms and implications for training and rehabilitation. Exp Gerontol. 2010 Jun;45(6):400-9. doi: 10.1016/j.exger.2010.03.008. Epub 2010 Mar 18.
Frontera WR, Hughes VA, Krivickas LS, Roubenoff R. Contractile properties of aging skeletal muscle. Int J Sport Nutr Exerc Metab. 2001 Dec;11 Suppl:S16-20. doi: 10.1123/ijsnem.11.s1.s16. No abstract available.
Frontera WR, Reid KF, Phillips EM, Krivickas LS, Hughes VA, Roubenoff R, Fielding RA. Muscle fiber size and function in elderly humans: a longitudinal study. J Appl Physiol (1985). 2008 Aug;105(2):637-42. doi: 10.1152/japplphysiol.90332.2008. Epub 2008 Jun 12.
Cadore EL, Rodriguez-Manas L, Sinclair A, Izquierdo M. Effects of different exercise interventions on risk of falls, gait ability, and balance in physically frail older adults: a systematic review. Rejuvenation Res. 2013 Apr;16(2):105-14. doi: 10.1089/rej.2012.1397.
Chen TC, Tseng WC, Huang GL, Chen HL, Tseng KW, Nosaka K. Superior Effects of Eccentric to Concentric Knee Extensor Resistance Training on Physical Fitness, Insulin Sensitivity and Lipid Profiles of Elderly Men. Front Physiol. 2017 Apr 10;8:209. doi: 10.3389/fphys.2017.00209. eCollection 2017.
Dias CP, Toscan R, de Camargo M, Pereira EP, Griebler N, Baroni BM, Tiggemann CL. Effects of eccentric-focused and conventional resistance training on strength and functional capacity of older adults. Age (Dordr). 2015 Oct;37(5):99. doi: 10.1007/s11357-015-9838-1. Epub 2015 Sep 15.
Enoka RM. Eccentric contractions require unique activation strategies by the nervous system. J Appl Physiol (1985). 1996 Dec;81(6):2339-46. doi: 10.1152/jappl.1996.81.6.2339.
Gault ML, Willems ME. Aging, functional capacity and eccentric exercise training. Aging Dis. 2013 Sep 25;4(6):351-63. doi: 10.14336/AD.2013.0400351.
Hanson ED, Srivatsan SR, Agrawal S, Menon KS, Delmonico MJ, Wang MQ, Hurley BF. Effects of strength training on physical function: influence of power, strength, and body composition. J Strength Cond Res. 2009 Dec;23(9):2627-37. doi: 10.1519/JSC.0b013e3181b2297b.
LaStayo P, Marcus R, Dibble L, Wong B, Pepper G. Eccentric versus traditional resistance exercise for older adult fallers in the community: a randomized trial within a multi-component fall reduction program. BMC Geriatr. 2017 Jul 17;17(1):149. doi: 10.1186/s12877-017-0539-8.
Lim JY. Therapeutic potential of eccentric exercises for age-related muscle atrophy. Integr Med Res. 2016 Sep;5(3):176-181. doi: 10.1016/j.imr.2016.06.003. Epub 2016 Jun 18.
Mueller M, Breil FA, Vogt M, Steiner R, Lippuner K, Popp A, Klossner S, Hoppeler H, Dapp C. Different response to eccentric and concentric training in older men and women. Eur J Appl Physiol. 2009 Sep;107(2):145-53. doi: 10.1007/s00421-009-1108-4. Epub 2009 Jun 20.
Orer GE, Guzel NA, Arslan E. Recovery levels after eccentric and concentric loading in maximal force. J Phys Ther Sci. 2016 Jun;28(6):1743-7. doi: 10.1589/jpts.28.1743. Epub 2016 Jun 28.
Raj IS, Bird SR, Westfold BA, Shield AJ. Effects of eccentrically biased versus conventional weight training in older adults. Med Sci Sports Exerc. 2012 Jun;44(6):1167-76. doi: 10.1249/MSS.0b013e3182442ecd.
Roig M, O'Brien K, Kirk G, Murray R, McKinnon P, Shadgan B, Reid WD. The effects of eccentric versus concentric resistance training on muscle strength and mass in healthy adults: a systematic review with meta-analysis. Br J Sports Med. 2009 Aug;43(8):556-68. doi: 10.1136/bjsm.2008.051417. Epub 2008 Nov 3.
Symons TB, Vandervoort AA, Rice CL, Overend TJ, Marsh GD. Effects of maximal isometric and isokinetic resistance training on strength and functional mobility in older adults. J Gerontol A Biol Sci Med Sci. 2005 Jun;60(6):777-81. doi: 10.1093/gerona/60.6.777.
Vaczi M, Nagy SA, Koszegi T, Ambrus M, Bogner P, Perlaki G, Orsi G, Toth K, Hortobagyi T. Mechanical, hormonal, and hypertrophic adaptations to 10 weeks of eccentric and stretch-shortening cycle exercise training in old males. Exp Gerontol. 2014 Oct;58:69-77. doi: 10.1016/j.exger.2014.07.013. Epub 2014 Jul 23.
Other Identifiers
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B-1705-397-004
Identifier Type: -
Identifier Source: org_study_id
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