Effect of Sarcopenia in Stroke Patients

NCT ID: NCT05671705

Last Updated: 2025-06-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

83 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-01-02

Study Completion Date

2024-12-27

Brief Summary

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Primary research purpose:

-Prospective study to screen post stroke patients with sarcopenia and evaluate its effect on recovery

Secondary research purpose:

* To determine the degree of sarcopenia and correlation with poor functional prognosis of stroke in the stroke patient group.
* To determine the degree of sarcopenia and correlation with dixon MRI of thigh muscle
* To evaluate surface EMG (SEMG)-based signals and correlation with sarcopenia
* To determine the degree of sarcopenia and correlation with brain morphometric changes

Detailed Description

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Patients with first-ever stroke will be enrolled and assessed for sarcopenia. The evaluation parameters will include standard sarcopenia parameters and also SEMG-based signals and imaging studies.

Conditions

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Stroke Sarcopenia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Stroke patients with sarcopenia

Group will be stratified according to gender

DEXA Scan

Intervention Type DIAGNOSTIC_TEST

Fu of diagnostic tests

Stroke patients without sarcopenia

Group will be stratified according to gender

DEXA Scan

Intervention Type DIAGNOSTIC_TEST

Fu of diagnostic tests

Interventions

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DEXA Scan

Fu of diagnostic tests

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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Serum biomarkers, SEMG signals and MRI changes

Eligibility Criteria

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Inclusion Criteria

* Patients 65 years of age or older, stroke patients with first onset within 4 weeks

Exclusion Criteria

* Patients who have not been evaluated for sarcopenia
* Patients with neuromuscular diseases other than stroke that may affect gait function
* Patients unable to conduct clinical trials according to instructions
* Patients with uncontrolled medical/surgical disease
* Patients with metal substances in the body such as cardiac pacemakers, cochlear implants, etc.
* Patients who have difficulty collecting blood
* Patients who are difficult to follow up after 6 months of onset due to moving to another area
* Patients who have Parkinson's disease, dementia, or have a history of neuromuscular diseases such as Guillain-Barré syndrome or myasthenia gravis
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Saint Vincent's Hospital, Korea

OTHER

Sponsor Role collaborator

The Catholic University of Korea

OTHER

Sponsor Role lead

Responsible Party

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Sun Im

MD., PhD.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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The Catholic University of Korea

Bucheon-si, Gyeonggi-do, , South Korea

Site Status

St. Vincent's Hospital

Suwon, , South Korea

Site Status

Countries

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South Korea

Other Identifiers

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VC22ONDI0185

Identifier Type: -

Identifier Source: org_study_id

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