Respiratory and Quadriceps Muscle Fatigability After an ICU Acquired Weakness

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-06-15

Study Completion Date

2024-02-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Muscle dysfunction can be lead to poor outcomes moreover ICU muscle weakness recovery are not correctly described.

The investigators aimed to assess the ability for quadriceps or respiratory muscles to repeat an effort at a maximal loading.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Early Assessment of Quadriceps Muscle Recovery by Dynamometry and 3D Ultrasound in Intensive Care Patients Under Invasive Mechanical Ventilation

NCT07069959

Intensive Care Unit Acquired Weakness Muscle Weakness

NOT_YET_RECRUITING

Muscle Function and Muscle Ultrasound in ICU

NCT04696497

Muscle Weakness

TERMINATED NA

Ultrasound to Evaluate the Quadriceps Muscle Wasting

NCT02562495

Severe Cerebral Pathology

COMPLETED NA

IMT Outcomes in Sufferers of Severe Walking Disabilities and Intensive Care Unit Acquired Weakness

NCT06210763

Intensive Care Unit Acquired Weakness

RECRUITING NA

Muscle Dysfunction in Critical Illness

NCT03717831

Critical Illness Intensive Care (ICU) Myopathy PICS +1 more

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

ICU Acquired Weakness

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Muscle evaluation

Repeated maximal voluntary contraction

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Mechanically ventilated at least at 24 Hours
* Maximal inspiratory pressure \< 30 centimeter of water
* MRC score \< 48/60

Exclusion Criteria

* Age \< 18 years
* Patients with neurological pathology or pre existing neuromuscular dysfunction
* Patient unable to walk 50 meters before ICU admission
* Patient with a thoracic or abdominal surgery
* Inability to carry out maximal voluntary contraction

Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No