Muscle Mass Loss in Critically Ill Patients.

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

104 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-03-25

Study Completion Date

2020-11-14

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of the study is to describe the change in muscle mass in critically ill patients. The study will examine rectus femoris cross sectional area with ultrasound and identify risk factors of this changes.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Longitudinal Changes in Muscle Mass After Intensive Care

NCT05531305

Critical Illness Muscle Loss

COMPLETED NA

Effects of Frailty, Sarcopenia and Muscle Wasting on Outcomes of Patients in the Surgical Intensive Care Unit

NCT02270502

Critical Illness Sarcopenia Muscle Wasting

COMPLETED

Nutritional Status, Muscle Wasting and Fraility in Intensive Care Patients

NCT04709198

Critical Illness Nutritional Disorder

COMPLETED

Muscle Mass and Body Composition

NCT03184623

Muscle Loss

COMPLETED

Characterising Changes in Muscle Quantity and Quality in Patients Requiring ECMO Oxygen During Critical Illness

NCT02995811

Critical Illness Intensive Care Units Extracorporeal Membrane Oxygenation

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The study will commence following the Approval by The Ethics Research Committee. All patients admitted to our ICU from the 1st of March 2019 to the 31st of August 2019 will be enrolled after fulfilling the inclusion criteria and in the absence of any exclusion criteria. Informed consent will be requested. Ultrasound measurement of rectus femoris cross sectional area will be performed in first 24 hours after admission to ICU.

Study data will be entered in study form. The ultrasound measurement will be repeated on day 7 of hospitalisation.

Changes in rectus femoris cross sectional area and potential risk factors will be analysed. The length of ICU length of stay and 28-day mortality will be also monitored.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Muscle Loss

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* age ≥18 years
* mechanical ventilation expected for at least 48 hours

Exclusion Criteria

* Clinical Frailty Score above 7 prior admission
* neuromuscular disease in previous medical history
* amputated lower extremities
* trauma of lower extremities involving tights
* age under 18 years
* inability to perform ultrasound examination
* death or discharge prior completion of protocol
* full verticalization prior completion of protocol

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No