Electromyography and Acceleromyography in Ventilated ICU Patients
NCT ID: NCT03778749
Last Updated: 2019-05-21
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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TERMINATED
NA
12 participants
INTERVENTIONAL
2019-01-25
2019-05-16
Brief Summary
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Detailed Description
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The stimulation pattern of both ulnar and facial nerves will be train-of-four (TOF) delivered every 1 minute, and the mean of three consecutive measurements will be calculated as the TOF% for that patient. Patients will be tested every 24 hrs, once a day, at the same time, over the 72 hrs the study will take place in the ICU.
Conditions
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Study Design
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NON_RANDOMIZED
SINGLE_GROUP
DIAGNOSTIC
NONE
Study Groups
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electromyographic NMT monitoring at the hand
In 20 mechanically ventilated ICU patients, TOF measurements will be performed every 24 hrs, once a day, at the same time, over the 72 hrs the study will take place in the ICU.
TOF measurements
The investigators will determine how the TOF% values vary in each individual patient, over time, in ICU.
acceleromyographic NMT monitoring at the hand
In 20 mechanically ventilated ICU patients, TOF measurements will be performed every 24 hrs, once a day, at the same time, over the 72 hrs the study will take place in the ICU.
TOF measurements
The investigators will determine how the TOF% values vary in each individual patient, over time, in ICU.
acceleromyographic NMT monitoring at the eyebrow
In 20 mechanically ventilated ICU patients, TOF measurements will be performed every 24 hrs, once a day, at the same time, over the 72 hrs the study will take place in the ICU.
TOF measurements
The investigators will determine how the TOF% values vary in each individual patient, over time, in ICU.
Interventions
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TOF measurements
The investigators will determine how the TOF% values vary in each individual patient, over time, in ICU.
Eligibility Criteria
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Inclusion Criteria
* expected to require mechanical ventilation for more than 72 hrs
Exclusion Criteria
* receive drugs interfering with NMT (e.g., aminoglycosides or magnesium)
18 Years
ALL
No
Sponsors
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Mayo Clinic
OTHER
Onze Lieve Vrouw Hospital
OTHER
Responsible Party
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Guy CAMMU
Principal Investigator
Principal Investigators
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Guy Cammu, MD,PhD
Role: PRINCIPAL_INVESTIGATOR
Onze-Lieve-Vrouw Ziekenhuis, Aalst, Belgium
Locations
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OLV Hospital
Aalst, , Belgium
Countries
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References
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Naguib M, Brull SJ, Johnson KB. Conceptual and technical insights into the basis of neuromuscular monitoring. Anaesthesia. 2017 Jan;72 Suppl 1:16-37. doi: 10.1111/anae.13738.
Cammu G, Neyens E, Coddens J, Van Praet F, De Decker K. Postoperative residual curarisation is still an issue when weaning patients in intensive care following cardiac surgery. Anaesth Intensive Care. 2018 Nov;46(6):634-636. No abstract available.
Other Identifiers
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2018/091
Identifier Type: -
Identifier Source: org_study_id
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