Muscle Function After Intensive Care

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

104 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-09-01

Study Completion Date

2018-04-30

Brief Summary

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Final objective of critical care is no longer only survival. The role of medical and paramedical teams should also be to restore functional capacities, autonomy and quality of life. What has been call "intensive care unit - acquired weakness" (ICU-AW) is associated to acute and long term increased mortality, prolonged ICU and hospital stay, prolonged duration of mechanical ventilation, altered quality of life in survivors and increased health-related costs. In order to target efficient secondary prevention and early rehabilitation, prompt identification of muscle weakness is crucial. Several methods, aiming to assess muscle mass, muscle strength or physical function, are described. Manual muscle testing using the Medical Research Council (MRC) scale is still the most commonly utilized tool to diagnose ICU-AW (MRC \<48/60). Dynamometry is an objective alternative and one of the most accurate clinimetric tool to assess muscle strength. Literature is overflowing with insufficiently standardized dynamometry data. Using the investigator's published standardized protocol of quadriceps strength (QS) assessment, this observational study aim to describe physical performances of CC patients and thus to define the weakest ones, by comparing them to surgical and healthy subjects.

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Detailed Description

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Conditions

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Critically Ill Colorectal Surgery Healthy Muscle Strength

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Critically ill patients

Patients who spent a minimum of 48h in ICU

Patient follow up

Intervention Type OTHER

Patient follow up during one month

Surgical patients

Patients who were scheduled for elective colorectal surgery

Patient follow up

Intervention Type OTHER

Patient follow up during one month

Healthy subjects

Healthy volunteers

Patient follow up

Intervention Type OTHER

Patient follow up during one month

Interventions

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Patient follow up

Patient follow up during one month

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Collaborative ICU patients with length of stay \> 48h
* Surgical patients scheduled for colorectal surgery
* Healthy subjects

Exclusion Criteria

* a score \> 1 or \< -1 on the Richmond Agitation and Sedation Scale (RASS)
* coma
* total hip or knee arthroplasty in the dominant limb
* unauthorized support on the dominant leg
* open wound located at the ankle's anterior face of the dominant leg
* pre-existing myopathy or polyneuropathy
* para- or tetraparesis, para- or tetraplegia
* refusal.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes