Dynamic Arterial Elastance During General Anesthesia Induction

NCT ID: NCT03910179

Last Updated: 2020-03-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

65 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-09-10

Study Completion Date

2021-04-30

Brief Summary

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This study evaluates if dynamic arterial elastance measured before general anesthesia induction can predict the occurrence of hypotension due to general anesthesia induction.

Detailed Description

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As general anesthetics may be responsible for vasodilation and cardiac depression, arterial hypotension after induction of general anesthesia is a common event and may contribute to an adverse outcome. Dynamic arterial elastance has been proposed as a functional parameter of arterial tone and studies showed that it was able to predict pressure response to fluid administration in fluid-responsive patients and the amount of mean arterial pressure riduction as a conseguence of noradrenaline dose reduction in critically ill patients.

Conditions

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Anesthesia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Patients that will be undergone to general anesthesia for surgery
* Patients that need mini-invasive cardiac output monitoring during surgery

Exclusion Criteria

* Age \<18 yo
* Pregnancy
* Arrhythmia
* Severe valvular diseases
* Uncorrectable alterations of arterial signal
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Università Politecnica delle Marche

OTHER

Sponsor Role lead

Responsible Party

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Abele Donati, MD

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Abele Donati, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Università Politecnica delle Marche

Locations

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Azienda ospedaliero Universitaria Ospedali Riuniti Ancona

Ancona, , Italy

Site Status RECRUITING

Countries

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Italy

Facility Contacts

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Abele Donati, MD, PhD

Role: primary

+390715964603

Other Identifiers

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CLRIA-AC01

Identifier Type: -

Identifier Source: org_study_id

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