Hemodynamic Changes After Anesthesia With Propofol: Study of Biomarkers
NCT ID: NCT02442232
Last Updated: 2016-08-26
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
65 participants
OBSERVATIONAL
2015-08-31
2016-05-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Hemodynamics During Induction of General Anesthesia With High and Low Propofol Dose.
NCT03861364
Hemodynamic Changes and Propofol Pharmacokinetic Variation During Anesthesia Induction and Knee-chest Positioning
NCT03961958
The Effect of Blood Pressure on Cerebral Blood Flow During Propofol Anesthesia
NCT03309917
Application of the Propofol Precise Infusion Model
NCT05158426
Efficacy and Safety Study of Two Propofol Formulations
NCT00506246
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
CASE_CONTROL
PROSPECTIVE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Normotensive
No interventions assigned to this group
Hypertensive taking ACEi
No interventions assigned to this group
Hypertensive not taking ACEi
No interventions assigned to this group
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* BMI lower 30 kg/m2
Exclusion Criteria
* Previous stroke
* Previous infarction
* Uncontrolled respiratory, renal, hepatic and hematological diseases.
40 Years
80 Years
ALL
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Conselho Nacional de Desenvolvimento Científico e Tecnológico
OTHER_GOV
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Gustavo Henrique Oliveira de Paula
PhD student
References
Explore related publications, articles, or registry entries linked to this study.
Oliveira-Paula GH, Coeli-Lacchini FB, Ferezin LP, Ferreira GC, Pinheiro LC, Paula-Garcia WN, Garcia LV, Tanus-Santos JE, Lacchini R. Arginase II polymorphisms modify the hypotensive responses to propofol by affecting nitric oxide bioavailability. Eur J Clin Pharmacol. 2021 Jun;77(6):869-877. doi: 10.1007/s00228-020-03059-9. Epub 2021 Jan 7.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
CNPq
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.